Evidence map›Paper›PMID 40548049›Full record

ArticleDrug, healthcare and patient safety2025

Adverse Effects Following Immunisation and Vaccine Hesitancy: A Qualitative Study in a South Indian District.

Retheesh Babu Gopalan, Bontha V Babu, Krishna Sarma S, Rooth P John

Abstract read
In one paragraph

Article in Drug, healthcare and patient safety, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Retheesh Babu GopalanICMR-National Institute of Virology, Kerala Unit, Alappuzha, 688 005, India.
Bontha V BabuDivision of Socio-Behavioural, Health Systems & Implementation Research, Indian Council of Medical Research, New Delhi, 110 029, India.ORCID 0000-0001-5096-2222
Krishna Sarma SICMR-National Institute of Virology, Kerala Unit, Alappuzha, 688 005, India.
Rooth P JohnICMR-National Institute of Virology, Kerala Unit, Alappuzha, 688 005, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Parental perceptions and concerns about vaccine safety and 'adverse effects following immunisation' (AEFI) are the reasons for vaccine hesitancy. This study aimed to understand how these vaccine-related concerns have become significant determinants of vaccine decision-making among non-vaccinating parents in the Alappuzha district of Kerala, India. The healthcare providers' views in this regard are also reported. Methods: This is a qualitative study. In-depth interviews were conducted with informants from 110 households having non-immunised/partly-immunised children. In addition, 18 healthcare providers were interviewed. Thematic analysis using the reflective thematic method was carried out. Results: Parents reported incidences of minor events of AEFI and are hesitant to continue vaccination in circumstances when children need medical treatment. AEFI incidents within the family have seriously hampered the trust in vaccines. Parents have concerns about multiple vaccinations and have misconceptions about the content of vaccines. Other concerns that lead to hesitancy are vaccine-related infertility, polio infection after polio vaccination and autism due to vaccination. Healthcare providers reported that there were no serious incidents that needed hospitalisation. Health workers opined that informing parents about AEFIs and preparing them is better. Conclusion: The study reported that AEFIs are a barrier to vaccine acceptance. It warrants the need to build trust in vaccines and the vaccination process. Transparent communication with the beneficiaries is crucial. AEFI monitoring and reporting should be an essential component of efforts to minimise vaccination hesitancy.

Indexed as

adverse effects following immunisationparental perceptionsqualitative researchvaccine hesitancy

Identifiers

PMID40548049
PMCPMC12180458

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.