ReviewFrontiers in pain research (Lausanne, Switzerland)2025
Sensory processing in medically unexplained pain syndrome. A systematic review.
Review in Frontiers in pain research (Lausanne, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Joint-level proprioceptive deficits and postural instability in Fibromyalgia: a biomechanical assessment using digital inclinometry and dynamic posturography.Frontiers in bioengineering and biotechnology · 2025Article
- A Review of Movement and Functional Impairments in Fibromyalgia: Implications for Targeted Treatment.Journal of pain research · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic pain is inherently multifactorial, with biological, psychological and social factors contributing to neuropathic pain (NP) and central sensitization (CS) syndromes. Comorbidity between functional disorders and the lack of clinical biomarkers adds to the challenge of diagnosis and treatment, leading to frustration for healthcare professionals and patients. The main objective of this review is to investigate the association between NP, CS syndromes and sensory processing disorders. A structured search was conducted on the PubMed database using the keywords Central Sensitization, Fibromyalgia, Complex Regional Pain Syndrome, and Neuropathic Pain, combined with the keywords Vision, Audition, Olfaction, Touch, Taste, and Proprioception. PubMed was chosen because it is accessible and user-friendly. Articles within the last five years, from 2018 to 2023, have been included. 380 studies on conditions of CS and sensory processing were identified. After applying inclusion and exclusion criteria, the number of retained papers was 78. There were a few emerging themes. Reduced sensory thresholds were found to be comorbid with chronic pain conditions, particularly those with a component of CS. Both cranial nerve and sensory evaluation examinations may prove helpful as potential biomarkers for diagnosis and for potential treatments.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.