Evidence map›Paper›PMID 40547836›Full record

ArticleWideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques2025

Influence of sex on the outcomes of uniportal video‑assisted thoracoscopic sympathicotomy for primary palmar hyperhidrosis.

Turkan Dubus, Gokce Cangel, Fatih Kesmezacar

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Article in Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

3 authors.

Turkan DubusDepartment of Thoracic Surgery, Health of Science University, Basakşehir Cam and Sakura City Hospital, Istanbul, Turkey.
Gokce CangelDepartment of Thoracic Surgery, Haseki Training and Research Hospital, Istanbul, Turkey.
Fatih KesmezacarImaging Program, Vocational School of Health Services, Istanbul University‑Cerrahpasa, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPrimary palmar hyperhidrosis (PPH) impairs the quality of life. Video‑assisted thoracoscopic sympathicotomy is an effective treatment method; however, the impact of sex on surgical outcomes accord‑ ing to the denervation level (T3 vs T3-T4 sympathicotomy) remains unclear.AIM This study investigated the efficacy, complications, and symptom relief rates of isolated T3 vs combined T3-T4 sympathicotomy for PPH, focusing on sex differences. MATERIALS AND

methodsA retrospective analysis of 327 patients undergoing bilateral uniportal video‑assisted thoracoscopic sympathicotomy for PPH between 2012 and 2022 was performed. The patients were divided into 2 groups depending on the procedure type (isolated T3 sympathicotomy [n = 167] vs T3-T4 combined sympathicotomy [n = 160]). Demographic data, procedure outcomes, and complications were compared.

resultsSuccess rates were 95.8% in the T3 sympathicotomy group and 93.8% in the T3-T4 sympathicotomy group, with no significant difference. The most common complication was dryness of the hands. The overall complication rate was lower in the T3 than in the T3-T4 sympathicotomy group (9.6% vs 14.4%; P = 0.04). Compensatory sweating occurred in 2.4% and 3.1% of the participants in the T3 and T3-T4 sympathicotomy groups, respectively (P = 0.52). The frequency of compensatory sweating, chest pain, and dryness of the hands was significantly higher in men. Age, sex, and duration of surgery had no independent influence on the occurrence of complications.

conclusionsIsolated T3 sympathicotomy is an effective and safe option for the treatment of PPH, and is associated with fewer complications than combined T3-T4 sympathicotomy. Higher complication rates in men emphasize the need for sex‑specific surgical planning and patient counseling.

Indexed as

palmar hyperhidrosissex differencesT3 and T3–T4 sympathicotomyuniportal video‑assisted thoracoscopic sympathicotomy

Identifiers

PMID40547836
PMCPMC12177343

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