Evidence map›Paper›PMID 40547806›Full record

ReviewExploration of targeted anti-tumor therapy2025

An overview of the feasibility of nanomedicine in pancreatic cancer theranostics.

Kyriakos Kokkinogoulis, Aristomenis Kollas, David Simeonidis, Pavlos Papakostas, Kalliopi Platoni, Efstathios P Efstathopoulos, Mersini Makropoulou

Abstract readReview
In one paragraph

Review in Exploration of targeted anti-tumor therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kyriakos KokkinogoulisDepartment of Physics, Faculty of Applied Mathematical and Physical Sciences, National Technical University of Athens, 15772 Athens, Greece.ORCID https://orcid.org/0009-0005-6478-9738
Aristomenis Kollas2 Oncology Clinic, Metropolitan General, 15562 Athens, Greece.
David Simeonidis2 Oncology Clinic, Metropolitan General, 15562 Athens, Greece.
Pavlos Papakostas2 Oncology Clinic, Metropolitan General, 15562 Athens, Greece.
Kalliopi Platoni2 Department of Radiology, Medical Physics Unit, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece.ORCID https://orcid.org/0000-0003-2977-7895
Efstathios P Efstathopoulos2 Department of Radiology, Medical Physics Unit, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece.ORCID https://orcid.org/0000-0003-2747-3353
Mersini MakropoulouDepartment of Physics, Faculty of Applied Mathematical and Physical Sciences, National Technical University of Athens, 15772 Athens, Greece.ORCID https://orcid.org/0000-0002-3720-4862

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic ductal adenocarcinoma (PDAC) is among the top causes of cancer-induced mortality, frequently diagnosed too late to be treated effectively, due to the poor prognosis and the limited successful therapeutic options. Apart from the conventional treatments, new multimodal therapies have emerged utilizing different scientific fields for the improvement of the survival and quality of patients' lives. The advancement of nanotechnology leads the way to more personalized medicine and the use of targeted theranostics carriers for deep-seated cancers such as PDAC. New nanotechnology innovations such as specialized photo-sensitizing drug nanocarriers, can effectively improve photodynamic therapy (PDT) of PDAC and enhance phototherapy's action through surface plasmon resonance phenomenon, as another recently re-emerged non- or minimally invasive possible treatment of such diseases. Despite the scientific advancements, significant hurdles remain and many parameters need to be examined. However, the novel application of nano-biophotonic techniques and the convergence of different science fields offer promise for the treatment of difficult-to-treat diseases, like PDAC.

Indexed as

Nanomedicinepancreatic cancerpersonalized medicinephotodynamic therapyphotothermal effectplasmonic photothermal therapy

Identifiers

PMID40547806
PMCPMC12179641

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.