Evidence map›Paper›PMID 40547793›Full record

ArticleFrontiers in microbiology2025

Dissemination of KPC-2-producing carbapenem-resistant

Cailing Wan, Meilan Li, Haojin Gao, Peiyao Zhou, Bingjie Wang, Junhong Shi, Li Shen, Weihua Han, Xinru Yuan, Jianbo Lv and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Multidrug-resistantNew microbes and new infections · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Cailing Wan *Department of Clinical Laboratory, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Meilan Li *Department of Clinical Laboratory, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Haojin Gao *Department of Clinical Laboratory, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Peiyao ZhouDepartment of Clinical Laboratory, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Bingjie WangDepartment of Clinical Laboratory, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Junhong ShiDepartment of Clinical Laboratory, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Li ShenDepartment of Clinical Laboratory, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Weihua HanDepartment of Clinical Laboratory, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Xinru YuanDepartment of Clinical Laboratory, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Jianbo LvDepartment of Clinical Laboratory, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Yu HuangDepartment of Clinical Laboratory, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Ying ZhouDepartment of Clinical Laboratory, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Fangyou YuDepartment of Clinical Laboratory, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The global emergence of carbapenem-resistant Methods: Seven separate clinical isolates were collected from hospitalized patients between January 2021 and March 2022. Bacterial isolates were identified, and antimicrobial susceptibility testing was conducted using the VITEK-2 compact automated system. Whole-genome sequencing (WGS) was performed on all seven isolates to confirm the presence of resistance genes. Additionally, a representative strain (G5) was selected for in-depth genomic characterization using long-read sequencing to analyze its genetic features and mobile genetic elements. Conjugation experiments were conducted to assess the transferability of the resistance plasmids. Results: All isolated strains were identified as ST792-type CRKP carrying bla Conclusion: This study characterizes the nosocomial dissemination of KPC-2-producing

Indexed as

carbapenem-resistant Klebsiella pneumoniaedisseminationmolecular epidemiologyST792whole-genome sequencing

Identifiers

PMID40547793
PMCPMC12179200

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.