Evidence map›Paper›PMID 40547562›Full record

ArticleJournal of cell communication and signaling2025

Cell line authentication and validation is a key requirement for

Ralf Weiskirchen, Jamie Almeida, Brahim Chaqour

Abstract readEditorial
In one paragraph

Article in Journal of cell communication and signaling, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Cell line authentication: a commercial service provider perspective.Frontiers in cell and developmental biology · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ralf WeiskirchenInstitute of Molecular Pathobiochemistry RWTH University Hospital Aachen Aachen Germany.ORCID https://orcid.org/0000-0003-3888-0931
Jamie AlmeidaBiosystems and Biomaterials Division National Institute of Standards and Technology Gaithersburg Maryland USA.ORCID https://orcid.org/0000-0001-5616-4029
Brahim ChaqourDepartment of Molecular Ophthalmology Perelman School of Medicine University of Pennsylvania Philadelphia Pennsylvania USA.ORCID https://orcid.org/0000-0002-8516-4324

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell lines are essential tools in biomedical research and drug discovery, often substituting for tissues or organs of origin. However, frequent misidentification and cross-contamination pose major quality control challenges, leading to unreliable data, hindering scientific progress, and impacting clinical translation. Even authenticated cell lines may undergo genetic and phenotypic changes over time, affecting experimental outcomes. To promote transparency, reproducibility, and rigor, the

Indexed as

cell line authenticationcell line nomenclatureJCCSmycoplasmaSTR profilingvalidation

Identifiers

PMID40547562
PMCPMC12181071

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.