ArticleWorld journal of gastrointestinal endoscopy2025
Pancreato-hepatobiliary neuroendocrine tumors diagnosed through endoscopic ultrasound: Clinical characteristics and factors associated with high-grade lesions.
Article in World journal of gastrointestinal endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Challenges in evaluating high-grade pancreato-hepato-biliary neuroendocrine tumors.World journal of gastrointestinal endoscopy · 2025Article
- Endoscopic ultrasonography as a comprehensive tool in the evaluation of pancreatic lesions.World journal of gastrointestinal endoscopy · 2025Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNeuroendocrine tumors (NETs) are an important type of neoplastic disease of the digestive tract. There is little data on NETs originating from the pancreato-hepatobiliary region of the digestive tract in Pakistan.
aimTo evaluate different types of pancreato-hepatobiliary NETs (PHB-NET) diagnosed with endoscopic ultrasound (EUS) and to identify factors associated with high-grade NETs.
methodsAll patients diagnosed with PHB-NET through EUS-guided biopsy were included in the study. The site of origin, histology, and grade of PHB-NETs were noted and factors associated with high-grade lesions were analyzed. SPSS, version 20.0 was used for statistical analysis.
resultsA total of 36 patients with PHB-NET were included. Males and females were equal in numbers,
conclusionThe most common site of PHB-NET detected through EUS was the pancreas. Although most were benign, about one-third were high-grade cancers. Insulinoma was the most common functioning tumor. NECs were associated with advanced age, extra-pancreatic origin, and small-cell histology.
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