ArticleFrontiers in endocrinology2025
The influence of ovarian cyst type and size on ovarian reserve markers: implications for fertility counseling and preservation strategy.
Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Radiomics and Artificial Intelligence in Ovarian Endometriosis Imaging: A Systematic Review and Critical Appraisal of Emerging Evidence.Bioengineering (Basel, Switzerland) · 2026Review
- Article
- The paradoxical association between endometrioma size and serum anti-Müllerian hormone levels in infertile women.Scientific reports · 2026Article
- The influence of fetal sex on preterm birth risk in gestational diabetes mellitus: A retrospective cohort study.Experimental and therapeutic medicine · 2026Article
- Changes in ovarian reserve function after laparoscopic ovarian cystectomy: a retrospective cohort study.Frontiers in surgery · 2026Article
- Does endometrioma diameter impact serum anti-Müllerian hormone levels? A systematic review and meta-analysis.Human reproduction open · 2026Article
- Circadian Biology and Gynecological Diseases: Genetic Mechanisms and Potential Therapeutic Targets Underlying the Causal Link Between Insomnia and Ovarian Cysts.International journal of women's health · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
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Abstract
Background: Ovarian cysts are common in reproductive-aged women and may affect ovarian reserve, thereby impacting fertility potential. This study aimed to evaluate the differential impact of various ovarian cyst types and sizes on ovarian reserve markers to inform individualized fertility care. Methods: A retrospective cohort study was conducted on 474 women classified into four groups: endometrioma, simple cyst, dermoid cyst, and controls without cysts. Serum anti-Müllerian hormone (AMH), follicle-stimulating hormone (FSH) levels, and antral follicle count (AFC) were assessed. Multivariate regression analyses adjusted for age and BMI were used to evaluate the independent effects of cyst type and size on ovarian reserve markers. Results: Compared to controls, women with ovarian cysts had significantly lower AMH and AFC levels and higher FSH levels (all p < 0.001). Endometriomas exerted the most profound negative impact, with the lowest AMH and AFC values and the highest FSH levels. Larger cysts were independently associated with greater reductions in AMH and AFC and increases in FSH levels. Conclusion: Both ovarian cyst type and size significantly influence ovarian reserve. Endometriomas and larger cysts are particularly detrimental. These findings highlight the need for personalized fertility counseling and early preservation strategies in affected women.
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