ArticleFrontiers in cardiovascular medicine2025
Dynamic change in maternal cardiac function during pregnancy.
Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Left Atrial Volumes and Strains in Healthy Mid-Term Pregnancy-A Detailed Investigation from a Three-Dimensional Speckle-Tracking Echocardiographic MAGYAR-Preg Study.Biomedicines · 2026Article
- Evaluation of cardiac strain parameters in pregnant women with and without iron deficiency anemia: a prospective case control study.BMC pregnancy and childbirth · 2025Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Pregnant women experience various physiological changes that, if uncompensated, may result in varying degrees of cardiac dysfunction, and adverse pregnancy outcomes. Left ventricular (LV) global longitudinal strain (GLS) and P-wave to A' duration on tissue Doppler imaging (PA-TDI) have been shown to be able to detect subtle cardiac dysfunction. Methods: The present study was a prospective cross-sectional study. A total of 506 healthy pregnant women were enrolled, including 149 during early pregnancy (before 13 weeks' gestation, T1 group), 99 during mid-pregnancy (14-27 weeks' gestation, T2 group), and 258 during late pregnancy (after 28 weeks' gestation, T3 group), while 172 age- and baseline weight-matched healthy nonpregnant women served as the control group (NPC group). Clinical and echocardiographic data of the subjects were collected. The difference in cardiac structure and function among the 4 groups were analyzed. Multivariate regression analysis was conducted to identify the independent factors influencing change in cardiac function. Results: The median age of the 4 groups were comparable [T1 group, 31.0 (28.5,34.0) years; T2 group, 31.0 (29.0,34.0) years; T3 group, 31.0 (29.0,34.0) years; the NPC group, 31.0 (28.0,34.0) years, Conclusion: Pregnant women show a trend toward decreased left ventricular systolic and diastolic function. PA-TDI and LV-GLS can be used to evaluate subtle change in left cardiac function in pregnant women.
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