Evidence map›Paper›PMID 40547388›Full record

ArticleMedical acupuncture2025

Manual Acupuncture for Improvement of Nasolabial Fold: A Quasi-Experimental Research.

Vera Nurmawati, Irma Nareswari, Ahmad Aulia Jusuf

Abstract read
In one paragraph

Article in Medical acupuncture, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Vera NurmawatiFaculty of Medicine, Medical Acupuncture Specialist Program, Universitas Indonesia, Jakarta, Indonesia.
Irma NareswariFaculty of Medicine, Medical Acupuncture Specialist Program, Universitas Indonesia, Jakarta, Indonesia.
Ahmad Aulia JusufMedical Acupuncture Clinic, Bandung City Regional General Hospital, Bandung, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The nasolabial folds are one of the most recognizable signs of aging in the midface. Acupuncture has been used widely for beauty therapy including facial rejuvenation and is known to be effective and have minimal side effects in reducing wrinkles. The aim of this study was to determine the changes in nasolabial fold after manual acupuncture for facial rejuvenation. Methods: This study is designed as a quasi-experimental or also called as one group pretest-posttest design involving 25 participants. Eligible patients will receive the same manual acupuncture therapy three times a week for 2 weeks. Manual acupuncture is performed at ST36. At the face, acupuncture is performed using the penetrating needling technique, from the superior edge of the arcus zygomaticus through ST2 toward LI20, on the zygomaticum through ST3 toward the middle of the nasolabial fold, on the inferior edge of the arcus zygomaticum through SI18 toward ST4, ST7 toward ST4, and at ashi point on the scalp along the temporal hairline at the m. temporoparietal. The outcomes are nasolabial length changes measured in millimeters, changes in the wrinkle severity rating scale (WSRS), and changes in the global aesthetic improvement scale (GAIS). The outcome will be evaluated at baseline, posttherapy, 2-week, and 4-week follow-up posttherapy. Results: The length of the nasolabial fold decreased after therapy with a mean change of 37.34%. There was one level of improvement on the WSRS after therapy. On the GAIS, there was an improvement of two to three levels after therapy. Conclusion: Nasolabial fold improved after receiving manual acupuncture therapy for facial rejuvenation.

Indexed as

acupuncturefacial rejuvenationnasolabial foldskin agingwrinklewrinkle severity rating scale

Identifiers

PMID40547388
PMCPMC12179375

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.