Evidence map›Paper›PMID 40547362›Full record

Articlenpj women's health2025

Endometriosis and autoimmunity: a large-scale case-control study of endometriosis and 10 distinct autoimmune diseases.

M Aziz, M A Beaton, M A Aziz, J Opoku-Anane, N Elhadad

Abstract read
In one paragraph

Article in npj women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

M AzizComputer Science, Columbia University, New York, New York, USA.
M A BeatonBiomedical Informatics, Columbia University, New York, NY USA.
M A AzizBiomedical Sciences, New York Institute of Technology College of Osteopathic Medicine, Old Westbury, NY USA.
J Opoku-AnaneObstetrics and Gynecology, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ USA.
N ElhadadComputer Science, Columbia University, New York, New York, USA.

Funding

PhendoPHL:A Data-Science Enabled Personal Health Library to Manage EndometriosisR01LM013043 · NLM · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ELHADAD, NOEMIE · 2019 to 2022
$1.4M
NLM NIH HHS R01 LM013043
6 · The paper itself

Abstract

In this study, we assessed if women with endometriosis have greater odds than matched controls of receiving an autoimmune diagnosis within two-years of their endometriosis diagnosis. We conducted a retrospective cohort study using two large-scale administrative claims databases (2010-2017), identifying 332,409 patients with endometriosis and 1,220,932 matched controls. Compared to matched controls, patients with endometriosis had an increased risk of being diagnosed with rheumatoid arthritis, Hashimoto's disease, systemic lupus erythematosus, multiple sclerosis, pernicious anemia, Sjogren's syndrome or myositis within two-years of their endometriosis diagnosis. The odds of receiving a diagnosis of at least one of the autoimmune conditions among patients with endometriosis were approximately two times greater than matched controls. Our study is the first to show a significant association between endometriosis and autoimmune conditions within a two-year diagnosis window, adding to growing evidence suggesting a potential link between endometriosis and autoimmunity, warranting investigation into shared mechanisms.

Indexed as

Reproductive disorders

Identifiers

PMID40547362
PMCPMC12176652

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.