Evidence map›Paper›PMID 40547358›Full record

ArticleCanadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR2025

Influence of conical-PEP breathing on exercise performance in patients with chronic obstructive pulmonary disease: A single-blind randomized crossover trial.

Nimit Kosura, Aung Aung Nwe, Chatchai Phimphasak, Worawat Chumpangern, Kongrit Sriya, Chulee Ubolsakka-Jones

Abstract read
In one paragraph

Article in Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nimit KosuraDepartment of Physical Therapy Prince of Songkla University.ORCID https://orcid.org/0000-0001-7660-8555
Aung Aung NweSchool of Physical Therapy Khon Kaen University.ORCID https://orcid.org/0009-0007-1311-6853
Chatchai PhimphasakSchool of Physical Therapy Khon Kaen University.
Worawat ChumpangernDepartment of Medicine Khon Kaen University.ORCID https://orcid.org/0000-0002-2564-6954
Kongrit SriyaDepartment of Family Medicine Nam-Phong Hospital.
Chulee Ubolsakka-JonesSchool of Physical Therapy Khon Kaen University.ORCID https://orcid.org/0000-0002-4471-8220

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Conical-positive expiratory pressure (conical-PEP) has been applied during exercise to improve exercise capacity, dynamic hyperinflation (DH), and dyspnea in COPD. However, evidence remains limited regarding the individualized selection of its resistor (orifice size) and its effects on exercise duration, DH development, and dyspnea. Method: A randomized crossover trial was conducted to evaluate the effects of conical-PEP. Participants performed spot marching exercise while breathing through a conical-PEP device with a mask, compared to a sham-PEP condition in which a similar mask was worn without the conical-PEP component. The conical-PEP resistor was selected to achieve the minimum required PEP level, calculated by the proposed formula, while ensuring that pressure did not exceed 35 cmH₂O. Exercise endurance time, end-exercise inspiratory capacity (IC) to assess DH, and dyspnea using the modified Borg scale were recorded. Results: Twenty moderate to severe COPD subjects (19 male, 1 female, age 67.40 ± 8.22 years, FEV1% predicted 56.05 ± 16.90) participated. Conical-PEP resulted in longer exercise time (4.98 ± 2.97 minutes) than sham-PEP (3.99 ± 2.19 minutes, p = 0.004). End-exercise IC was significantly better in conical-PEP (1.51 [1.24, 1.85] L) than sham-PEP (1.42 [1.16, 1.84] L, Conclusion: Conical-PEP with minimum required PEP level improves exercise capacity, delays DH development, and delays dyspnea onset in COPD patients.

Indexed as

COPDdynamic hyperinflationdyspneaexercise timepositive expiratory pressure

Identifiers

PMID40547358
PMCPMC12179794

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.