Evidence map›Paper›PMID 40547345›Full record

ReviewMayo Clinic proceedings. Innovations, quality & outcomes2025

Exercise Testing Characteristics, Safety, and Quality in Patients with Cancer: A Systematic Review.

Elisabeth Edvardsen, Tormod Skogstad Nilsen, Robert Novo, Michael Curry, Scott C Adams, Konstantina Matsoukas, Justin Huang, Jasme Lee, Chaya Moskowitz, Lee W Jones and 1 more

Abstract readReview
In one paragraph

Review in Mayo Clinic proceedings. Innovations, quality & outcomes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Elisabeth EdvardsenDepartment of Pulmonary Medicine, Oslo University Hospital, Oslo, Norway.
Tormod Skogstad NilsenDepartment of Pulmonary Medicine, Oslo University Hospital, Oslo, Norway.
Robert NovoMemorial Sloan Kettering Cancer Center, New York, NY.
Michael CurryMemorial Sloan Kettering Cancer Center, New York, NY.
Scott C AdamsCancer Fatigue Services, Toronto, ON, Canada.
Konstantina MatsoukasMemorial Sloan Kettering Cancer Center, New York, NY.
Justin HuangHunter College, New York, NY.
Jasme LeeMemorial Sloan Kettering Cancer Center, New York, NY.
Chaya MoskowitzMemorial Sloan Kettering Cancer Center, New York, NY.
Lee W JonesMemorial Sloan Kettering Cancer Center, New York, NY.
Jessica M ScottMemorial Sloan Kettering Cancer Center, New York, NY.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Objective: To evaluate exercise testing (ExT) characteristics, safety, and methodological quality in oncology settings. Patients and Methods: In this systematic review, we searched electronic databases (PubMed, Embase, CINAHL, and Cochrane Library) from inception to March 2024. Studies using ExT to evaluate cardiorespiratory fitness or functional capacity in adults with a history of cancer were included. Summary data including ExT characteristics (eg, modality, cardiorespiratory fitness, and functional capacity results), safety (eg, adverse events [AE]), and methodological quality (eg, guideline adherence) was evaluated. Results: A total of 642 unique studies with 94,960 patients (58.6±9.9 years; 49% women) were included. Among the 26 ExT modalities used, the maximal cardiopulmonary exercise test (CPET) with measurement of gas exchange (n=284, 40%) and the 6-minute walk test (6MWT) (n=240, 34%) were the most frequently performed. Of the 284 studies that conducted CPET, n=204 (72%) studies reported peak oxygen consumption in mL·kg Conclusion: The findings of this systematic review indicate that CPET with gas exchange and field-based tests such as the 6MWT are widely used; however, future research should prioritize improving safety monitoring, appropriate test selection, and methodological consistency to enhance the applicability of ExT in oncology care.

Identifiers

PMID40547345
PMCPMC12182365

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.