ArticleThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale2025
Bacteriological Spectrum and Drug Resistance Among Patients Associated With Bloodstream Infection in Intensive Care Units in the Affiliated Hospital of Jiaxing University From 2021 to 2023.
Article in The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Bloodstream infections (BSI) in ICU settings are associated with high morbidity, mortality, and healthcare costs. The ICU environment, with its high use of invasive devices and immunocompromised patients, fosters an increased risk for multidrug resistance (MDR) pathogens, complicating treatment strategies. Understanding the epidemiology and resistance patterns in these settings is essential for improving patient outcomes and guiding appropriate antimicrobial stewardship practices. This study retrospectively analyzed data from 640 blood culture samples collected in the ICU of the Affiliated Hospital of Jiaxing University between January 2021 and December 2023. The blood samples were appropriately collected and cultured. Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry was employed to identify the isolated strains. Antimicrobial sensitivity was assessed using the VITEK2 system, the Epsilometer test (E-test), and the Kirby-Bauer disk diffusion method. All statistical analyses were conducted using IBM SPSS Statistics 22.0. A total of 391 bacterial pathogens (61.1%) were isolated. The predominant pathogens causing BSI were Gram-negative bacteria. The most prevalent pathogens during the period were coagulase-negative
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