ArticleTherapeutic advances in infectious disease
Prevalence and factors associated with hyperuricemia among people living with HIV in Uganda: a cross-sectional study at a tertiary hospital in Uganda.
Article in Therapeutic advances in infectious disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Association between a high total cholesterol-to-high-density lipoprotein cholesterol ratio and hyperuricemia among patients with hypertension: A cross-sectional study from central Uganda.The Journal of international medical research · 2026Article
- Urate dysregulation (hyperuricemia and gout) among people living with HIV: A protocol for a systematic review and meta-analysis.PloS one · 2026Article
- Development and internal validation of a risk model for hyperuricemia among people living with HIV in Hangzhou, China: a retrospective longitudinal cohort study.Frontiers in endocrinology · 2026Article
- Correlation Between Anthropometric Measurements with Cardiometabolic Biomarkers and Ten-Year Cardiovascular Risk Score Among People with HIV in Uganda.HIV/AIDS (Auckland, N.Z.) · 2025Article
- Magnitude of Hyperuricemia and Its Associated Factors Among People Living with Human Immunodeficiency Virus Who Enrolled in First-Line Antiretroviral Therapy in Amhara Region, Ethiopia.Journal of the International Association of Providers of AIDS CareArticle
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5 authors.
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Abstract
Background: Hyperuricemia is associated with an elevated risk of cardiovascular diseases (CVD) among people with HIV (PLWH). However, there is a paucity of studies examining the factors associated with hyperuricemia among PLWH in sub-Saharan Africa. Objective: This study aimed to determine the prevalence and factors associated with hyperuricemia among PLWH at a tertiary hospital in Uganda. Design: We conducted a cross-sectional study among PLWH receiving antiretroviral therapy (ART) at the HIV clinic at Kiruddu National Referral Hospital in Kampala, Uganda. Methods: Data were collected using a structured questionnaire, anthropometric and blood pressure measurements, and analysis of fasting blood glucose, blood lipids, glycated hemoglobin, and serum uric acid of blood samples from participants. Modified Poisson regression with robust standard errors was used to assess factors associated with hyperuricemia. Statistical significance was set at Results: Among 390 PLWH, the mean (SD) age was 41.4 (12.3) years, and 209 (53.6%) were female. A total of 360 (92.3%) were on dolutegravir-based ART regimens, and 94.7% (306/323) were virally suppressed (viral load < 1000 copies/mL). The prevalence of hyperuricemia was 21.3% (83/390). Current alcohol use (adjusted prevalence ratio (aPR) = 2.07, 95% CI: 1.26, 3.41, Conclusion: One in five PLWH had hyperuricemia in this study. Alcohol use was identified as a potential modifiable risk factor for hyperuricemia. While alcohol cessation programs are needed to mitigate the risk of hyperuricemia, studies should explore the effect of hyperuricemia on lung function among PLWH.
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