Evidence map›Paper›PMID 40547278›Full record

ArticleACG case reports journal2025

Malignancy Masquerade: Inclusion-Negative Herpes Simplex Virus Rectal Pseudotumor in a Patient With HIV.

Aaron C Nguyen, Moez Karim Aziz, Frederick B Peng, Nathan Spezia-Lindner, Georgia Huffman, Stefanos Millas, Roberto Cavazos

Abstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aaron C NguyenDepartment of Internal Medicine, Baylor College of Medicine, Houston, TX.ORCID https://orcid.org/0000-0002-0885-8891
Moez Karim AzizDepartment of Internal Medicine, Baylor College of Medicine, Houston, TX.
Frederick B PengDepartment of Gastroenterology and Hepatology, Baylor College of Medicine, Houston, TX.
Nathan Spezia-LindnerDepartment of Gastroenterology and Hepatology, Baylor College of Medicine, Houston, TX.
Georgia HuffmanDepartment of Pathology, Baylor College of Medicine, Houston, TX.
Stefanos MillasDepartment of Surgery, University of Texas Health Science Center, Houston, TX.
Roberto CavazosDepartment of Internal Medicine, Baylor College of Medicine, Houston, TX.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herpes simplex virus (HSV) infections are among the most common sexually transmitted infections in humans. However, atypical presentations may occur in immunocompromised patients such as nodules, condylomatous masses, or hypertrophic lesions. Even further, HSV pseudotumors with negative histologic staining have been incompletely discussed in previous literature. We present a 51-year-old patient with a history of well-controlled HIV-1, who presented with a rectal mass, originally concerning for underlying bacterial infection or malignancy. Despite negative HSV immunohistochemical staining on biopsy, the mass improved with empiric intravenous acyclovir therapy, ultimately suggestive of a rectal HSV pseudotumor.

Indexed as

Herpes simplex virusHIVHSVHSV pseudotumorhuman immunodeficiency virusimmunocompromisedmalignancyrectal mass

Identifiers

PMID40547278
PMCPMC12180815

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.