Evidence map›Paper›PMID 40547250›Full record

ArticleTherapeutic advances in gastroenterology2025

Discordance between patients' perception and endoscopic assessment of disease activity in ulcerative colitis.

Boilève Juliette, Trang-Poisson Caroline, Flamant Mathurin, Bouguen Guillaume, Goronflot Thomas, Freyssinet Marie, Kerdreux Elise, Bourreille Arnaud, Le Berre Catherine

Erratum issuedAbstract read
In one paragraph

Article in Therapeutic advances in gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Boilève JulietteInstitut des Maladies de l'Appareil Digestif, Hépato-Gastro-Entérologie et Assistance Nutritionnelle, Inserm CIC 1413, Nantes Université, CHU Nantes, Nantes, France.
Trang-Poisson CarolineInstitut des Maladies de l'Appareil Digestif, Hépato-Gastro-Entérologie et Assistance Nutritionnelle, Inserm CIC 1413, Nantes Université, CHU Nantes, Nantes, France.
Flamant MathurinService de gastroentérologie, Jules Verne Clinic, Nantes, France.
Bouguen GuillaumeInstitut NUMECAN (Nutrition Metabolism and Cancer), CHU Rennes, Univ Rennes, INSERM, CIC1414, Rennes, France.
Goronflot ThomasClinique des données, Inserm CIC 1413, CHU Nantes, Nantes, France.
Freyssinet MarieService de gastroentérologie, Jules Verne Clinic, Nantes, France.
Kerdreux EliseCentre de recherche clinique, Jules Verne Clinic, Nantes, France.
Bourreille ArnaudInstitut des Maladies de l'Appareil Digestif, Hépato-Gastro-Entérologie et Assistance Nutritionnelle, Inserm CIC 1413, Nantes Université, CHU Nantes, Nantes, France.
Le Berre CatherineInstitut des Maladies de l'Appareil Digestif, Hépato-Gastro-Entérologie et Assistance Nutritionnelle, Inserm CIC 1413, Nantes Université, CHU Nantes, 1 place Alexis Ricordeau, Nantes F-44000, France.ORCID https://orcid.org/0000-0002-1124-2019

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Discrepancies between symptoms and endoscopy exist in patients with ulcerative colitis (UC). Most studies focused on patient-reported outcomes-2 rather than their overall perception of disease activity. Objectives: The objectives were to assess the concordance between the patient global assessment (PtGA) and the endoscopic evaluation, to analyse the factors associated with agreement and to describe the concordance between the patient's and the physician's perception of UC activity. Design: Prospective, observational study. Methods: Patients with UC were consecutively included at the time of flexible sigmoidoscopy. The concordance between the Mayo endoscopic subscore (MES) and the PtGA was evaluated. The factors related to concordance were investigated, including the inflammatory bowel disease (IBD)-Disk items that were completed by all patients. Results: Out of 104 analysable patients, 32.7% demonstrated complete alignment with the MES. The more the disease was objectively active, the more the patients were concordant, as reflected by the statistically significant differences between concordant and discordant patients in the median (interquartile range) MES (2 (1-2) vs 1 (0-2), respectively ( Conclusion: Discrepancies between patient-reported disease activity and endoscopy are prevalent in UC. In addition to rectal bleeding, abdominal pain and bowel urgency may be more accurate to reflect clinical disease activity than stool frequency.

Indexed as

endoscopyinflammatory bowel diseasepatient global assessmentpatient-reported outcomes

Identifiers

PMID40547250
PMCPMC12182626

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.