Evidence map›Paper›PMID 40547210›Full record

ArticleRSC advances2025

Encapsulation of progesterone in reishi mushroom composite for optimized hormone replacement and targeted anticancer therapy.

Samar M Mahgoub, Abdullah S Alawam, Hassan A Rudayni, Ahmed A Allam, Aya Shaban, Esraa Khaled, Aya M Mokhtar, Sahar Abdel Aleem Abdel Aziz, Rehab Mahmoud

Abstract read
In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Samar M MahgoubMaterials Science and Nanotechnology Department, Faculty of Postgraduate Studies for Advanced Sciences, Beni-Suef University Egypt miramar15@yahoo.com.
Abdullah S AlawamDepartment of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU) Riyadh 11623 Saudi Arabia asalawam@imamu.edu.sa HARUDAYNI@imamu.edu.sa aallam@imamu.edu.sa.
Hassan A RudayniDepartment of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU) Riyadh 11623 Saudi Arabia asalawam@imamu.edu.sa HARUDAYNI@imamu.edu.sa aallam@imamu.edu.sa.
Ahmed A AllamDepartment of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU) Riyadh 11623 Saudi Arabia asalawam@imamu.edu.sa HARUDAYNI@imamu.edu.sa aallam@imamu.edu.sa.
Aya ShabanFaculty of Pharmacy, Cairo University Egypt ayaelhuseani@gmail.com.
Esraa KhaledBiotechnology Department, Faculty of Post-Graduate Studies for Advanced Sciences, Beni-Suef University Beni-Suef Egypt esraakhaledmahmoud10_pg@psas.bsu.edu.eg.
Aya M MokhtarHydrogeology and Environment Department, Faculty of Earth Sciences, Beni-Suef University Beni-Suef 62511 Egypt aya2451999mo@gmail.com.
Sahar Abdel Aleem Abdel AzizDepartment of Hygiene, Zoonoses and Epidemiology, Faculty of Veterinary Medicine, Beni-Suef University Beni-Suef 62511 Egypt abdelaziz.sahar@yahoo.com.
Rehab MahmoudChemistry Department, Faculty of Science, Beni-Suef University Beni-Suef 62511 Egypt rehabkhaled@science.bsu.edu.eg.ORCID https://orcid.org/0000-0003-2274-2016

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conventional hormone replacement therapy (HRT) and hormone-dependent cancer treatments face significant challenges, including poor bioavailability, rapid metabolism, and adverse side effects of progesterone, as well as limited targeting efficiency and systemic toxicity. To address these issues, this study develops an innovative progesterone-reishi mushroom (

Identifiers

PMID40547210
PMCPMC12179686

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.