Evidence map›Paper›PMID 40547147›Full record

ArticleWorld journal of gastrointestinal oncology2025

Unravelling the potential of plasma DNA methylation in the detection and surveillance of esophageal cancer.

Jitesh Arora, Mahmoud Nassar, Bahaaeldin Baraka

Abstract readLetter
In one paragraph

Article in World journal of gastrointestinal oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jitesh AroraDepartment of Geriatric Medicine, Nottingham University Hospitals NHS Trust, Nottingham NG7 2UH, United Kingdom.
Mahmoud NassarDepartment of Medicine, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, New York, NY 14203, United States.
Bahaaeldin BarakaDepartment of Oncology, Nottingham University Hospitals NHS Trust, Nottingham NG5 1PB, United Kingdom. bahaabaraka@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Esophageal cancer (EC) continues to pose a significant clinical challenge due to the absence of a reliable early detection method, leading to late-stage diagnoses and poor patient outcomes. The recent study by Liu

Indexed as

Esophageal cancerPlasma DNA methylationScreening

Identifiers

PMID40547147
PMCPMC12179958

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.