ArticleEnvironmental science: atmospheres2025
Laboratory development and validation of vapor phase PFAS methods for soil gas, sewer gas, and indoor air.
Article in Environmental science: atmospheres, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Vapor-Phase Detection of Perfluoroalkyl Acids using Amplifying Fluorescent Polymers.Small methods · 2026Article
- The hidden fluorine: a critical review of analytical methods for unmasking PFAS and closing fluorine mass balance in environmental samples.Analytical and bioanalytical chemistry · 2026Review
- Practical Guidance on Selecting Analytical Methods for PFAS in Semiconductor Manufacturing Wastewater.ACS measurement science au · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
There is no standard sampling and analysis method for vapor phase per- and polyfluoroalkyl substances (PFAS) that can be routinely applied to soil gas, sewer/conduit gas, and indoor air samples. We have validated a thermal desorption GC/MS/MS method for the measurement of a set of fluorotelomer alcohols and perfluorooctanesulfonamides collected on multi-bed sorbent tubes. Applications to perfluorocarboxylic acids were also evaluated since there is debate regarding under what circumstances these compounds could be observed moving into gas phase. Perfluorooctanoic acid (PFOA) met Method TO-17 calibration requirements when calibrated using National Institute of Standards and Technology (NIST) traceable standard solutions introduced through the thermal desorption system and using multiple reaction monitoring (MRM) transitions based on precursor mass ions identified in the PFOA spectra. However, subsequent detailed studies suggested that PFOA was decomposing during the thermal desorption sample introduction step when comparing two alternative GC/MS sample introduction techniques. The primary peak resulting from the thermal desorption of PFOA standard had spectra consistent with perfluoro-1-heptene (PFHp-1), suggesting that a degradation reaction was occurring. Therefore, the identification of the PFCA compounds in this method is currently subject to a potential positive interference from the corresponding perfluoroalkene and other thermally labile PFAS. Thus, it may be beneficial to limit the application of the thermal desorption GC/MS/MS method to the fluorotelomer alcohols and perfluorooctanesulfonamides and use a parallel solvent extraction approach to quantify the PFCA-related compounds. Method validation including desorption efficiency, second source verification, storage stability and method detection limit tests were successfully completed for the fluorotelomer alcohols and perfluorooctanesulfonamides target analytes.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.