ArticleComputational and structural biotechnology journal2025
Granular osteoconductive biopolymer and predictive analysis of its physical property changes in maxillofacial surgery.
Article in Computational and structural biotechnology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Dry bulk fractions of osteoconductive granular biopolymers (OGB) are a common choice for addressing jawbone defects. These, in conjunction with an insulating biological membrane, form bioengineered scaffold structures. In the recipient site, the OGB fraction undergoes biotransformation, morphing from a bulk granular fraction into a stable conglomerate. The biotransformation of the OGB fraction is a physical process initiated by the biological environment of the recipient site. This process is characterized by granule compaction due to reduced intergranular space volume, leading to an uncontrolled decrease in the planned volume of the OGB. This is one of the causes of postoperative complications. This study aims to identify prognostic indicators that characterize the dynamics of changes in the physical property of the total volume of the OGB fraction following the addressing of a jawbone defect (in the postoperative period). To minimize these limitations, the study substantiated the use of prognostic indicators that can characterize the behavior of the entire volume of the OGB fraction within the recipient site during the postoperative period. The study presents the true adsorption capacity (AC
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