Evidence map›Paper›PMID 40546997›Full record

ArticleOrthopaedic journal of sports medicine2025

Comparative Outcomes After Bone-Patellar Tendon-Bone Allograft Reconstruction of the Anterior Cruciate Ligament Using Various Allograft Processing Protocols.

Benjamin Miltenberg, Randall Timothy Kreulen, Gaston Davis, William L Johns, Rahul Muchintala, Jonathan Berg, Fotios P Tjoumakaris, Kevin B Freedman

Abstract read
In one paragraph

Article in Orthopaedic journal of sports medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Benjamin MiltenbergThe Rothman Institute at Thomas Jefferson, Bryn Mawr, Pennsylvania, USA.
Randall Timothy KreulenThe Rothman Institute at Thomas Jefferson, Bryn Mawr, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-5140-0958
Gaston DavisThe Rothman Institute at Thomas Jefferson, Bryn Mawr, Pennsylvania, USA.
William L JohnsThe Rothman Institute at Thomas Jefferson, Bryn Mawr, Pennsylvania, USA.
Rahul MuchintalaThe Rothman Institute at Thomas Jefferson, Bryn Mawr, Pennsylvania, USA.
Jonathan BergThe Rothman Institute at Thomas Jefferson, Bryn Mawr, Pennsylvania, USA.
Fotios P TjoumakarisThe Rothman Institute at Thomas Jefferson, Bryn Mawr, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-1013-7735
Kevin B FreedmanThe Rothman Institute at Thomas Jefferson, Bryn Mawr, Pennsylvania, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Graft choice in anterior cruciate ligament reconstruction (ACLR) is determined by surgeon preference, patient factors, and graft characteristics. An allograft is a viable option with benefits such as decreased operative times and no donor site morbidities, and it can be the preferred graft choice in certain patient populations. Despite this, there is no established standard for allograft processing. Purpose: To determine whether allograft processing techniques influence the risk of graft failure, patient-reported outcomes, and revision surgery in patients undergoing ACLR. Study Design: Cohort study; Level of evidence, 3. Methods: Consecutive patients from 3 fellowship-trained sports medicine surgeons undergoing ACLR with patellar tendon allografts from January 1, 2016, to January 1, 2022, were identified. Descriptive data, mechanism of injury, graft processing technique, revision history, and patient-reported outcome scores were collected. The primary endpoint was aseptic failure as defined by graft rupture on magnetic resonance imaging. Statistical analysis was performed with the χ Results: A total of 189 patients who underwent ACLR and met the inclusion/exclusion criteria were identified, with 103 Musculoskeletal Transplant Foundation (MTF), 55 Allowash XG, and 31 BioCleanse allografts. The mean age of patients was 43.4 ± 10.5 years, and 60.9% were women. No significant difference was observed between the groups with regard to sex and body mass index ( Conclusion: Bone-patellar tendon-bone allografts processed using BioCleanse, Allowash XG, and the MTF protocol had similar rates of graft failure and postoperative IKDC scores. Although underpowered, the data suggest that each of these techniques can be used safely with low failure rates and good functional outcomes.

Indexed as

allograftanterior cruciate ligamentfailureInternational Knee Documentation Committeeoutcomes

Identifiers

PMID40546997
PMCPMC12179472

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.