ReviewClinical, cosmetic and investigational dermatology2025
Gray Hair: From Preventive to Treatment.
Review in Clinical, cosmetic and investigational dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Integrative Phenotypic and Transcriptomic Dynamics of Hair Follicle Development and Fur Quality in Rex Rabbits.Animal genetics · 2026Article
- A proteoglycan-based topical treatment for hair greying:Frontiers in medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aging is an inevitable natural process, with gray hair being one of its most visible signs. Hair graying holds psychosocial importance and is an excellent model for studying human pigmentation and aging in an accessible mini-organ. This phenomenon results from decreased melanin production in hair follicles, influenced by genetic, environmental, and lifestyle factors. Gray hair often poses aesthetic concerns and can be accelerated by environmental stressors, lifestyle choices, and nutritional deficiencies. Given the variation in onset and prevalence of gray hair, this study explores the underlying biological factors-namely, genetics, oxidative stress, and hormonal changes-to inform better prevention and treatment strategies. Recent advancements in prevention and treatment, such as topical melanin stimulants, antioxidants, dietary supplements, and low-level laser therapy (LLLT), offer promising approaches to managing gray hair. Understanding gray hair comprehensively-encompassing biological, psychological, and social dimensions-provides valuable insights into the aging process and can enhance overall well-being while addressing the stigma associated with aging. Our comprehensive analysis reveals that while graying correlates with certain health conditions, its primary significance is physiological rather than pathological. This understanding is essential for healthcare providers and the public to approach graying with scientific objectivity rather than social prejudice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.