Evidence map›Paper›PMID 40546875›Full record

ArticleIbrain2025

Severe relapse after cessation of immunosuppressive therapy in a patient with co-occurrence of neuromyelitis optica spectrum disorder and Sjögren's syndrome: A case report.

Man-Min Zhu, Zu-Cai Xu, Chang-Yin Yu, Hao Huang

Abstract read
In one paragraph

Article in Ibrain, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Man-Min ZhuDepartment of Neurology Affiliated Hospital of Zunyi Medical University Zunyi China.
Zu-Cai XuDepartment of Neurology Affiliated Hospital of Zunyi Medical University Zunyi China.
Chang-Yin YuDepartment of Neurology Affiliated Hospital of Zunyi Medical University Zunyi China.
Hao HuangDepartment of Neurology Affiliated Hospital of Zunyi Medical University Zunyi China.ORCID 0000-0001-7739-275X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuromyelitis optica spectrum disorder (NMOSD) is a group of autoimmune disorders characterized by inflammatory involvement of the optic nerve, spinal cord, and central nervous system. NMOSD is often associated with other autoimmune disorders, including Sjogren's syndrome (SS). While NMOSD typically occurs at a peak in young or older individuals, the coexistence of NMOSD and SS in a youngster is rare. Here, we presented a case of a 14-year-old girl with NMOSD and SS who responded well to immunosuppressive therapy but experienced a severe relapse after discontinuation of therapy. We described the clinical course of a case over 8 years, underscoring the importance of long-term treatment for NMOSD and SS. This case, along with the review of relevant literature, will raise awareness of this type of disease and facilitate early diagnosis and treatment to avoid serious sequelae.

Indexed as

immunosuppressive therapyneuromyelitis optica spectrum disorderrelapse childSjogren's syndrome

Identifiers

PMID40546875
PMCPMC12177671

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.