ArticleVeterinarni medicina2021
Comparative effectiveness of interventions for treating interdigital necrobacillosis in cattle: A network meta-analysis.
Article in Veterinarni medicina, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Clinical Efficacy of a Single Intravenous Regional Limb Perfusion with Marbofloxacin versus Ceftiofur Sodium to Treat Acute Interdigital Phlegmon in Dairy Cows.Animals : an open access journal from MDPI · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to comparatively evaluate the efficacy of different antimicrobial agents against interdigital necrobacillosis (IN) in cattle to identify the treatment with the greatest benefit. A network meta-analysis was used to synthesise empirical results from randomised controlled trials. Four studies with five interventions for 565 animals were included. The meta-analysis found no significant differences between the risk ratios for the antimicrobials versus placebo. However, ceftiofur sodium administered intramuscularly at a dose of 1.0 μg/kg body weight every 24 h for 3 days showed a better clinical response than 6.6 μg of oxytetracycline, 2.5 μg of tulathromycin, the placebo and 0.1 μg of ceftiofur sodium. The results show the best efficacy for 6.6 μg of oxytetracycline and 1.0 μg of ceftiofur sodium. Nevertheless, the latter is likely to be superior to oxytetracycline in terms of its pharmacodynamic and pharmacokinetic properties. Thus, 1.0 μg of ceftiofur sodium appears to provide the best therapeutic activity against IN in cattle. Further well-designed studies are required.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.