ArticleJournal of oral biology and craniofacial research
An umbrella review of systematic reviews/meta-analyses evaluating the antimicrobial activity of various nanoparticles on orthodontic materials & components.
Article in Journal of oral biology and craniofacial research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: White spot lesions (WSLs) are a prevalent issue during fixed orthodontic treatment. Orthodontic materials, such as wires, brackets, and adhesives, often create an environment that promotes microbial growth, particularly from acidogenic bacteria like Streptococcus mutans, leading to enamel demineralization. Traditional preventive measures include fluoride treatments and meticulous oral hygiene, but integrating antimicrobial nanoparticles into orthodontic materials offers a promising alternative. This umbrella review evaluates the antimicrobial efficacy of nanoparticles incorporated into orthodontic materials by assessing evidence from systematic reviews and meta-analyses. Various nanoparticles, including ZnO, Ag, and TiO Materials and method: A literature search was conducted across PubMed, Google Scholar, The Cochrane Library, and LILACS, yielding one hundred and sixty-seven articles after removing duplicates. Following abstract and title screening, twenty-seven studies were selected for full-text review, and nine were included in the qualitative analysis. This review adheres to PRISMA guidelines and is registered with PROSPERO (CXXXXXXXXXXXX2). Results: The studies indicate that incorporating AgNP into orthodontic adhesives enhances antimicrobial activity but exhibits high heterogeneity, necessitating more in vivo studies. TiO
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