Evidence map›Paper›PMID 40546651›Full record

ArticleClinicoEconomics and outcomes research : CEOR2025

Medicare Savings for Seizure Drugs by Adopting the Mark Cuban Cost Plus Drug Company Model.

Tim Smith, Alec Young, Cameron O'Brien, Jacob Duncan, Matthew Rashid, Trevor Magee, Kyle Fitzgerald, Matt Vassar

Abstract read
In one paragraph

Article in ClinicoEconomics and outcomes research : CEOR, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tim SmithOffice of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.
Alec YoungOffice of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.ORCID 0000-0003-1947-1534
Cameron O'BrienOffice of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.ORCID 0009-0001-8661-7073
Jacob DuncanOffice of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.
Matthew RashidOffice of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.
Trevor MageeOffice of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.
Kyle FitzgeraldOffice of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.
Matt VassarOffice of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Epilepsy is a lifelong diagnosis, often requiring pharmacologic management. Despite the chronicity of this disorder, there has been a rise in medication cost over the years. To address this, Mark Cuban Cost Plus Drug Company (MCCPDC) has created a more affordable option to obtain patients' prescriptions. Focusing on epileptic medication, this study examines the potential cost saving benefit of MCCPDC compared to Medicare Part D plans. Methods: We conducted a cross-sectional review identifying the prices of anticonvulsants available on MCCPDC compared to the 2021 Medicare Part D spending data. Prices for dispensing and shipping fees were recorded for the minimum quantity (30ct) and maximum quantity (90ct). We compared standardized unit prices for 30 and 90-day periods between Medicare and MCCPDC drugs. Results: Of the 16 anti-seizure medications shared between MCCPDC and Medicare, Medicare spending reached nearly $1 billion. Analyzing 30ct prescriptions, we found potential savings in 60% of the drugs, amounting to $172 million when comparing individual drug costs on MCCPDC to Medicare. However, when averaged across all 30ct drugs, MCCPDC prices were 14.85% higher than Medicare, indicating that higher costs for certain drugs offset the savings from others. For 90ct prescriptions, savings were $373 million in 80% of drugs, a 31.63% reduction compared to Medicare prices. Conclusion: Our study highlights the potential savings with MCCPDC, especially among the 90ct medications, demonstrating that a cheaper alternative to chronic medications is possible if the pricing of MCCPDC is used. We recommend that physicians educate patients on MCCPDC and their specific medications to find more accessible pricing. MCCPDC could alleviate financial burdens and enhance access to essential medications for patients, especially in the context of the Medicare-enrolled population.

Indexed as

anticonvulsantcosteconomicsMark Cubanpharmacyseizures

Identifiers

PMID40546651
PMCPMC12182730

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.