ArticleCureus2025
Rapidly Evolving Cervical Dermatofibrosarcoma Protuberans With Deep Muscle Infiltration: A Rare and Aggressive Presentation.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dermatofibrosarcoma protuberans (DFSP) is a rare, low-grade sarcoma that typically presents as a slow-growing cutaneous nodule or plaque. We report a highly unusual case of DFSP involving the neck, which demonstrated rapid enlargement, necrosis, and deep muscle infiltration. A 45-year-old man presented with a large, bleeding cervical tumor that had evolved over two years. Imaging revealed extensive involvement of the neck and shoulder musculature without distant metastasis. Histopathologic evaluation confirmed the diagnosis of DFSP. Given the tumor's inoperability, treatment with imatinib was initiated, resulting in marked tumor regression. This case highlights an atypical presentation of DFSP in terms of both location and clinical behavior. It underscores the importance of repeated histologic assessment in the face of rapid progression, the role of imaging in surgical planning, and the value of targeted therapy when surgical options are limited.
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Registered trials
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