ArticleCureus2025
Dengue Hemorrhagic Fever Complicated by Complete Atrioventricular Block: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dengue virus (DENV) infection is a common mosquito-borne disease with a broad clinical spectrum ranging from mild febrile illness to severe manifestations such as dengue haemorrhagic fever (DHF) and dengue shock syndrome. While hematologic and vascular complications are well-documented, cardiac involvement, such as conduction abnormalities, is less well-known but potentially fatal. A 53-year-old male with a five-day history of fever, fatigue, and dizziness presented in hemodynamic instability with severe bradycardia and hypotension. An ECG showed complete heart block, requiring the urgent insertion of a temporary pacemaker. Transthoracic echocardiogram demonstrated mildly reduced left ventricular systolic function (left ventricular ejection fraction = 45%). Laboratory investigations revealed thrombocytopenia with a platelet count of 109 × 10⁹/L. The patient had no known allergic conditions. Based on the clinical presentation and high index of suspicion, a dengue test was performed, confirming the infection through positive IgM serology and reverse transcriptase-polymerase chain reaction, which identified the DENV-2 serotype. Despite supportive care, the patient did not recover a normal cardiac rhythm and ultimately required a permanent pacemaker. This case highlights the potential for complete heart block as a severe complication of DHF.
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