Evidence map›Paper›PMID 40546611›Full record

ArticleCureus2025

Obesity-Associated Cancers: A United States Cancer Statistics (USCS) Database Analysis.

Jane N Nwafor, Alexander S Figueroa, Okelue E Okobi, Gift Ojukwu, Edamisan J Fanegan, Robert Nyamekye-Affel, Blessing O Oyewole, Oluwatobiloba Omotunde, Grace N Mamah, Nneka Muoghalu

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jane N NwaforInternal Medicine, University of the District of Columbia, Washington, DC, USA.
Alexander S FigueroaMedicine, University of the East Ramon Magsaysay Memorial Medical Center (UERMMMC) College of Medicine, Quezon City, PHL.
Okelue E OkobiFamily Medicine, IMG Research Academy and Consulting LLC, Homestead, USA.
Gift OjukwuGeneral Practice, Leeds Teaching Hospitals NHS Trust, Leeds, GBR.
Edamisan J FaneganPost Heart Catheterisation, RWJBarnabas Health, Newark, USA.
Robert Nyamekye-AffelInternal Medicine, St. Patrick's Hospital, Kumasi, GHA.
Blessing O OyewoleFamily Medicine, Northfield Family Health, Canada, CAN.
Oluwatobiloba OmotundeInternal Medicine, American International School of Medicine, Atlanta, USA.
Grace N MamahFamily and Community Medicine, University of Nigeria College of Medicine, Enugu, NGA.
Nneka MuoghaluPublic Health, Liverpool School of Tropical Medicine, University of Liverpool, Liverpool, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity is a well-established risk factor for various cancers, contributing to significant public health burdens. Disparities in obesity-associated cancer incidence exist across racial, age, and geographic groups, necessitating targeted prevention and intervention strategies.

objectiveThe aim of this study is to analyze the incidence rates of obesity-associated cancers across different racial, age, and geographic groups in the United States from 2017 to 2021, identifying key disparities to inform public health interventions.

methodsA retrospective analysis of cancer incidence data from national registries was conducted. Age-adjusted incidence rates (per 100,000 population) were calculated across racial/ethnic groups, age cohorts, and US states. Descriptive statistics and confidence intervals were used to assess disparities.

resultsBlack, non-Hispanic individuals had the highest obesity-associated cancer incidence (184.8 per 100,000), followed by American Indian/Alaska Native populations (179.3 per 100,000). Incidence rates increased with age, peaking at 75-79 years (788.7 per 100,000 overall). Geographically, Midwestern and Southern states exhibited higher incidence rates, with West Virginia reporting the highest (188.3 per 100,000) and Nevada the lowest (149.5 per 100,000). These findings highlight significant racial, age, and regional disparities.

conclusionThe study underscores the need for targeted public health strategies, including enhanced screening, culturally tailored interventions, and policy-driven approaches to address obesity and its related cancer risks. Future research should explore individual-level risk factors and effective interventions to promote equitable healthcare access and improved cancer outcomes.

Indexed as

databaseobesityobesity-associated cancerretrospective studyuscs

Identifiers

PMID40546611
PMCPMC12181978

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.