ArticleCureus2025
Sodium-Glucose Cotransporter-2 Inhibitors and Euglycemic Diabetic Ketoacidosis: A Case Series of Three Post-surgical Patients.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed.
- Retinal Outcomes in Diabetes: Antihyperglycemic Therapy, EWDR, and Perioperative Considerations.Biomedicines · 2026Review
- Euglycemic Diabetic Ketoacidosis: Clinical Suspicion and Diagnosis.Clinical medicine insights. Endocrinology and diabetes · 2026Review
- SGLT2 Inhibitors: From Structure-Effect Relationship to Pharmacological Response.International journal of molecular sciences · 2025Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sodium-glucose cotransporter 2 (SGLT2) inhibitors are a class of commonly prescribed medications used in diabetes management for both their cardiovascular and renal benefits. However, as a class, SGLT2 inhibitors have a known side effect risk for ketoacidosis, including the rarer version called euglycemic diabetic ketoacidosis (DKA). We present three cases of euglycemic DKA postoperatively, in patients who were on SGLT2 inhibitors for type 2 diabetes mellitus. A DKA protocol was initiated for all three patients, and after treatment with fluid and insulin therapy, all patients recovered. All three were restarted on their SGLT2 inhibitor upon discharge. Based on this limited experience, we recommend close monitoring of postoperative patients on SGLT2 inhibitors to allow early detection of euglycemic DKA. Larger trials are needed to determine the exact, optimal timing of restarting SGLT2 inhibitors postoperatively.
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