Evidence map›Paper›PMID 40546575›Full record

ArticleCureus2025

Trends of Sinusitis-Associated Orbital Cellulitis in Pediatric Patients: A Retrospective Cohort Review.

Saleh Khurshied, Hira G Shah, Aisha Babar, Asma Afsar, Muhammad A Zahid, Mehrun Nisa

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Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Saleh KhurshiedOtolaryngology - Head and Neck Surgery, Pakistan Institute of Medical Sciences, Islamabad, PAK.
Hira G ShahOphthalmology, Alshifa Trust Eye Hospital, Rawalpindi, PAK.
Aisha BabarOtolaryngology - Head and Neck Surgery, University Hospitals Plymouth NHS Trust, Plymouth, GBR.
Asma AfsarOtolaryngology - Head and Neck Surgery, Pakistan Institute of Medical Sciences, Islamabad, PAK.
Muhammad A ZahidOphthalmology, Monash Health, Clayton, AUS.
Mehrun NisaMedicine and Surgery, Pakistan Institute of Medical Sciences, Islamabad, PAK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objective Orbital cellulitis is mostly associated with sinusitis. The pediatric cases have a peculiar clinical presentation and variability with respect to different factors like season, type of sinus involved, and number of sinuses involved. In this study, we aimed to analyze the trends of sinusitis-associated orbital cellulitis in pediatric patients, which, we believe, would help physicians in managing these patients. Material and methods We retrospectively reviewed the discharge records of 74 pediatric patients treated at the ENT-Head and Neck Surgery Department of the Pakistan Institute of Medical Sciences, Islamabad, Pakistan, between January 2015 and March 2025. The study included only inpatients aged 1-14 years who were diagnosed with orbital cellulitis secondary to associated sinusitis, confirmed by CT findings. Data on patients' demographics, clinical characteristics, month of presentation, type of sinusitis, and sinuses involved were recorded. Trends in the form of results were presented in tables and figures. Results The mean age of the cohort was 7 ± 4.3 years, with 47 (63.51%) being male and 27 (36.49%) female. Out of all the cases admitted, 70 (94.6%) had fever at the time of presentation, 74 (100%) had headache, 74 (100%) had pain, and 74 (100%) had chemosis and periorbital edema. Of the patients, 41 (55.40%) had ophthalmoplegia, 29 (39.19%) had facial edema, and 14 (18.92%) had reduced eyesight. There were 49 (66.22%) known cases of chronic sinusitis. Of the total number of cases, 29 (39.19%) occurred in the winter, 18 (24.32%) in the spring, 17 (22.97%) in the summer, and 10 (13.51%) in the fall. Of the total cases, 23 (31.08%) involved a single sinus, 46 (62.16%) involved two or more sinuses, and five (6.76%) involved pansinusitis. In cases with single sinus sinusitis, the ethmoid was most frequently involved (72.4%). Conclusions We observed that cases of sinusitis-associated orbital cellulitis had a peculiar presentation including headache, discomfort, chemosis, periorbital pain, and fever. Orbital cellulitis was more frequently linked to chronic rhinosinusitis. Orbital cellulitis linked to sinusitis peaked in the winter and spring. The most frequent cause of orbital cellulitis in children was ethmoidal sinusitis. Orbital cellulitis was typically caused by sinusitis involving two or more sinuses.

Indexed as

clinical findingscommon factorsorbital celluliitssinusitistrends analysis

Identifiers

PMID40546575
PMCPMC12179345

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