ArticleCureus2025
Atypical Presentation of Small Bowel Neuroendocrine Carcinoma Leading to Acute Obstruction.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
4 authors.
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Abstract
Rare neoplasms called neuroendocrine tumors (NETs) develop from intestinal enterochromaffin cells. They commonly produce symptoms through the secretion of serotonin along with other vasoactive peptides, resulting in carcinoid syndrome, characterized by cutaneous flushing and diarrhea. NETs are a very aggressive type of cancer, for which prognostic factors are lacking. They are also rarely found in males and young adults. Carcinoid tumors make up an atypical and intricate disease spectrum with various clinical features. The combination of etoposide and carboplatin can enhance overall survival in complex WHO stage 3 neuroendocrine carcinoma with regional lymph node involvement and a generally poor prognosis. However, in the absence of distant metastasis and with a relatively fair performance index, this treatment may be more effective. In this instance, we report a neuroendocrine tumor case that presented unusually as an acute intestinal obstruction. The patient had resection and anastomosis of the small bowel of the affected region along with the surrounding mesentery.
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