Evidence map›Paper›PMID 40546567›Full record

ArticleCureus2025

Kounis Syndrome Without Systemic Allergy: A Subtle Presentation of Stent Thrombosis.

Giovanni Paolella, Viktoriya Bikeyeva, Mae Leef, George C Michalopoulos, Joseph Adams, Andrii Labchuk, Adib Chaus

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Giovanni PaolellaInternal Medicine, Advocate Lutheran General Hospital, Park Ridge, USA.
Viktoriya BikeyevaInternal Medicine, Advocate Lutheran General Hospital, Park Ridge, USA.
Mae LeefInternal Medicine, Advocate Lutheran General Hospital, Park Ridge, USA.
George C MichalopoulosInternal Medicine, Advocate Lutheran General Hospital, Park Ridge, USA.
Joseph AdamsCardiology, Advocate Lutheran General Hospital, Park Ridge, USA.
Andrii LabchukCardiology, Advocate Lutheran General Hospital, Park Ridge, USA.
Adib ChausCardiology, Advocate Lutheran General Hospital, Park Ridge, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kounis Syndrome, or allergic acute coronary syndrome, is a rare cause of myocardial ischemia triggered by hypersensitivity reactions. Type III Kounis Syndrome, involving in-stent thrombosis following an allergic insult, is particularly rare and underrecognized. We report the case of a 67-year-old woman with a known contrast allergy who developed inferior ST-elevation myocardial infarction (STEMI) complicated by early stent thrombosis, suspected to be due to type III Kounis Syndrome. This case underscores the importance of maintaining a high index of suspicion for allergic triggers in acute coronary syndromes and considering contrast-sparing strategies in high-risk individuals.

Indexed as

allergic acute coronary syndromecontrast allergykounis syndromest-elevation myocardial infarctionstent thrombosistype iii kounis

Identifiers

PMID40546567
PMCPMC12182279

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.