Evidence map›Paper›PMID 40546542›Full record

ArticleCureus2025

Sciatic Nerve Neuropathy Secondary to Sacral Pressure Ulcer Following COVID-19: A Case Report.

Jorge F Tuma, Pedro Henrique Marte de Arruda Sampaio, Paulo Tuma

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jorge F TumaGeneral Surgery, Hospital Israelita Albert Einstein, São Paulo, BRA.
Pedro Henrique Marte de Arruda SampaioNeurology, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (HC-FMUSP), São Paulo, BRA.
Paulo TumaPlastic Surgery, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (HC-FMUSP), São Paulo, BRA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of a previously healthy 25-year-old man who developed severe SARS-CoV-2 infection requiring prolonged mechanical ventilation. Following extubation, he presented with peripheral sensory deficits and a sacral pressure ulcer. He was later admitted to our service with fever and a Grade IV ulcer, which required surgical debridement, negative pressure wound therapy, and definitive reconstruction using a V-Y gluteal flap. Examination of the right leg at admission demonstrated a neuropathic pain pattern, with neurological evaluation and imaging confirming distal sensorimotor polyneuropathy and chronic proximal sciatic neuropathy. Treatment with pregabalin led to complete resolution of symptoms, with no neurological deficit or residual pain identified during follow-up. This report suggests a plausible intersection between pressure-related and neurological complications in critically ill COVID-19 patients and highlights the importance of early preventive strategies such as frequent repositioning and multidisciplinary ICU care.

Indexed as

case reportcovid-19gluteus maximus flapicu complicationsnegative pressure therapyneuropathic painpressure ulcerreconstructive surgerysciatic neuropathyv-y flap

Identifiers

PMID40546542
PMCPMC12182710

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.