Evidence map›Paper›PMID 40546536›Full record

ArticleCureus2025

Primitive Sjögren's Syndrome Revealed by Bilateral Pleurisy in a Teenager: An Unexpected Case.

Meriem Rhazari, Ikram Sadki, Hiba Ramdani, Afaf Thouil, Hatim Kouismi

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Meriem RhazariPulmonology, Faculty of Medicine and Pharmacy of Oujda, Mohammed VI University Hospital, Mohammed First University, Oujda, MAR.
Ikram SadkiInternal Medicine, Faculty of Medicine and Pharmacy of Oujda, Mohammed VI University Hospital, Mohammed First University, Oujda, MAR.
Hiba RamdaniMedicine, Faculty of Medicine and Pharmacy of Oujda, Mohammed VI University Hospital, Mohammed First University, Oujda, MAR.
Afaf ThouilPulmonology, Faculty of Medicine and Pharmacy of Oujda, Mohammed VI University Hospital, Mohammed First University, Oujda, MAR.
Hatim KouismiPulmonology, Faculty of Medicine and Pharmacy of Oujda, Mohammed VI University Hospital, Mohammed First University, Oujda, MAR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary Sjögren's syndrome (PSS) is a rare autoimmune disease in children and adolescents. The initial pleural manifestations are exceptional. We report the case of a 16-year-old adolescent hospitalized for bilateral chest pain with pleurisy. The initial diagnosis of tuberculosis was suspected due to the clinical context and local endemicity, but microbiological and histological examinations were negative. The presence of anti-Sjögren's syndrome type A (anti-SSA) antibodies and a salivary gland biopsy confirming chronic sialadenitis allowed for the diagnosis of PSS. Management by corticosteroid therapy resulted in a significant clinical improvement. Although rare, PSS should be considered in the differential diagnosis of lymphocytic pleurisy, especially when anti-infective treatments fail. Pleuropulmonary manifestations are poorly described and can delay the diagnosis. This report highlights the diversity of presentations of PSS and the importance of a multidisciplinary approach for early diagnosis, allowing for improved prognosis of systemic complications.

Indexed as

anti-ssa/ro antibodiesauto immune diseaseautoimmunitybilateral pleurisyprimitive sjögren's syndrome

Identifiers

PMID40546536
PMCPMC12179558

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.