Evidence map›Paper›PMID 40546502›Full record

ArticleCureus2025

Acute Thyroid Swelling After Fine-Needle Aspiration in von Willebrand Disease: Case Report and Literature Review.

Takanobu Saheki, Toshihiro Kobayashi, Kensaku Fukunaga, Hitomi Imachi, Koji Murao

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Takanobu SahekiEndocrinology and Metabolism, Faculty of Medicine, Kagawa University, Kagawa, JPN.
Toshihiro KobayashiEndocrinology and Metabolism, Faculty of Medicine, Kagawa University, Kagawa, JPN.
Kensaku FukunagaEndocrinology and Metabolism, Faculty of Medicine, Kagawa University, Kagawa, JPN.
Hitomi ImachiEndocrinology and Metabolism, Faculty of Medicine, Kagawa University, Kagawa, JPN.
Koji MuraoEndocrinology and Metabolism, Faculty of Medicine, Kagawa University, Kagawa, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fine-needle aspiration cytology (FNAC) can cause rare complications, including acute transient thyroid swelling (ATTS). We report a 71-year-old female with von Willebrand disease (VWD) who developed rapid thyroid enlargement post-FNAC. Ultrasonography showed hypoechoic areas without blood flow, suggesting interstitial edema rather than hematoma. The swelling resolved within 12 hours with conservative management. Neuropeptide and histamine release may contribute to this phenomenon. This case highlights the importance of coagulation assessment and monitoring in FNAC for bleeding disorders. Recognizing hypoechoic areas without blood flow on ultrasound (US) may aid in distinguishing edema from hematoma. Further studies are needed to clarify the mechanism.

Indexed as

acute thyroid swellingfine-needle aspiration cytologyhematomavasodilatory substancesvon willebrand disease

Identifiers

PMID40546502
PMCPMC12180099

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.