Evidence map›Paper›PMID 40546407›Full record

ArticleJournal of inflammation research2025

IL-33 Participates in

Min Zhou, Lili Zhou, Junbo Liu, Shaohui Yu

Abstract read
In one paragraph

Article in Journal of inflammation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Inflammatory landscape ofFrontiers in immunology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Min ZhouDepartment of Gynecology, Changchun University of Chinese Medicine Affiliated Hospital, Changchun, Jilin, People's Republic of China.
Lili ZhouDepartment of Obstetrics, Changchun University of Chinese Medicine Affiliated Hospital, Changchun, Jilin, People's Republic of China.
Junbo LiuDepartment of Gynecology, Changchun University of Chinese Medicine Affiliated Hospital, Changchun, Jilin, People's Republic of China.
Shaohui YuDepartment of Gynecology, Changchun University of Chinese Medicine Affiliated Hospital, Changchun, Jilin, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Bacterial vaginosis (BV) is a common gynecological disease characterized by an abnormal increase in vaginal secretions, odor and itching. The pathogenesis of BV is not fully understood, but it is believed that the disruption of the mucosal immune system plays a key role. We investigated the role of IL-33 in preventing BV and explored the mechanism by which IL-33 regulates intravaginal IgA. Methods: Protein levels of IL-33 and IgA, and the pH value of vaginal secretions in healthy donors and patients with BV (14 vs 14) were determined by ELISA. Results: IL-33 and IgA were significantly decreased in vaginal secretions of patients with BV. IL-33 deficiency aggravated BV induced by Conclusion: IL-33 prevents

Indexed as

bacterial vaginosisG. vaginalisIgAIL-33TGF-β

Identifiers

PMID40546407
PMCPMC12182232

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.