Evidence map›Paper›PMID 40546379›Full record

ArticleIndian journal of sexually transmitted diseases and AIDS

A study comparing the efficacy of 25% podophyllin resin versus cryotherapy in the treatment of anogenital warts - What is old still holds good!

Shreya Srinivasan, N R Vignesh, G Sukanya, K Manoharan, S Gayathri, R N Raksha

Abstract read
In one paragraph

Article in Indian journal of sexually transmitted diseases and AIDS. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shreya SrinivasanDepartment of Dermatology, Venereology and Leprosy, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India.
N R VigneshDepartment of Dermatology, Venereology and Leprosy, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India.
G SukanyaDepartment of Dermatology, Venereology and Leprosy, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India.
K ManoharanDepartment of Dermatology, Venereology and Leprosy, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India.
S GayathriDepartment of Dermatology, Venereology and Leprosy, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India.
R N RakshaDepartment of Dermatology, Venereology and Leprosy, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Context: Human papillomavirus types 6 and 11 are the most prevalent strains that produce anogenital warts. Both cryotherapy and podophyllin have approved modalities in the treatment of anogenital warts. Aim: The aim of this study was to determine the treatment outcome following cryotherapy compared to podophyllin in the treatment of anogenital warts. Settings and Design: This was an observational study conducted in a tertiary care hospital. Materials and Methods: All patients diagnosed clinically with anogenital warts were recruited after obtaining informed consent and with due consideration of the inclusion and exclusion criteria. A brief history taking and examination was done. Patients were segregated into two groups based on the treatment received, which was either cryotherapy or podophyllin once a week for 6-week duration. Treatment response was assessed every week based on various scoring systems. Statistical Analysis Used: Results were analyzed using statistical software SPSS version 20.0. Results: Both cryotherapy and podophyllin showed similar efficacy, with 92.3% of patients in each group showing complete resolution of the lesions at the end of this study. It was also found that participants in the podophyllin group required 3.50 ± 1.67 weeks for complete clearance, while the cryotherapy group required only 2.08 ± 0.99 weeks. Both groups exhibited an equal proportion of adverse effects, which were not statistically significant. Conclusion: While both cryotherapy and podophyllin were equally effective in treating anogenital warts, cryotherapy showed a slightly faster resolution than podophyllin. Based on the overall findings, while both options can be provided to the patient, podophyllin still holds good in resource-poor settings where cryotherapy is not always available.

Indexed as

Anogenital wartscryotherapypodophyllin

Identifiers

PMID40546379
PMCPMC12180862

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.