Evidence map›Paper›PMID 40546303›Full record

ArticleBMJ neurology open2025

Time to endovascular thrombectomy for acute ischaemic stroke in language other than English (LOTE) communities in South-Western Sydney.

Vivek Pidugun, Daniel Wardman, Peter Thomas, Helen Badge, Jing Ji, Chushuang Chen, Timmy Pham, Andrew K Cheung, Nathan Manning, Christopher Blair and 6 more

Abstract read
In one paragraph

Article in BMJ neurology open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

16 authors.

Vivek PidugunNeurology, Liverpool Hospital, Liverpool, New South Wales, Australia.ORCID https://orcid.org/0009-0003-1612-4956
Daniel WardmanNeurology, Liverpool Hospital, Liverpool, New South Wales, Australia.
Peter ThomasNeurology, Liverpool Hospital, Liverpool, New South Wales, Australia.
Helen BadgeSouth Western Sydney Clinical School, University of New South Wales Medicine & Health, Sydney, New South Wales, Australia.
Jing JiIngham Institute for Applied Medical Research, Liverpool, New South Wales, Australia.
Chushuang ChenSouth Western Sydney Clinical School, University of New South Wales Medicine & Health, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0001-6014-846X
Timmy PhamNeurology, Liverpool Hospital, Liverpool, New South Wales, Australia.
Andrew K CheungSouth Western Sydney Clinical School, University of New South Wales Medicine & Health, Sydney, New South Wales, Australia.
Nathan ManningSouth Western Sydney Clinical School, University of New South Wales Medicine & Health, Sydney, New South Wales, Australia.
Christopher BlairNeurology, Liverpool Hospital, Liverpool, New South Wales, Australia.
Cecilia Cappelen-SmithNeurology, Liverpool Hospital, Liverpool, New South Wales, Australia.
Longting LinSouth Western Sydney Clinical School, University of New South Wales Medicine & Health, Sydney, New South Wales, Australia.
Suzanne J HodgkinsonNeurology, Liverpool Hospital, Liverpool, New South Wales, Australia.
Alan McDougallNeurology, Liverpool Hospital, Liverpool, New South Wales, Australia.
Mark ParsonsNeurology, Liverpool Hospital, Liverpool, New South Wales, Australia.
Dennis CordatoNeurology, Liverpool Hospital, Liverpool, New South Wales, Australia.ORCID https://orcid.org/0000-0001-8447-6644

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Access to endovascular thrombectomy (EVT) for acute ischaemic stroke (AIS) and the outcome disparities in culturally and linguistically diverse (CALD) populations are understudied. South-Western Sydney (SWS), characterised by high prevalence of CALD populations, provides an ideal setting to explore these disparities. This study aimed to assess whether being born in a country where English is not the primary language ('language other than English'; LOTE) affects access to EVT and outcomes for acute ischaemic stroke while also identifying demographic risk factors influencing stroke severity and outcomes. Methods: A retrospective cohort study was conducted on consecutive patients with AIS who underwent EVT at Liverpool Hospital, Sydney, from 2018 to 2023. Participants were categorised based on country-of-origin Australia/New Zealand/United Kingdom or LOTE. Primary outcomes included time metrics-onset-to-arrival (OTA) and arrival-to-puncture (ATP)-and 3-month modified Rankin Score (mRS). Statistical analyses included multivariate logistic regression to evaluate predictors of functional outcomes. Results: Of 911 EVT referrals, 721 patients were included. LOTE patients (50.3%) were more likely to have diabetes mellitus (30% vs 16%; p<0.001) and presented with higher stroke severity (median National Institutes of Health Stroke Scale (NIHSS) 17 vs 14; p<0.001). They also experienced shorter ATP (158 vs 174 min; p=0.006). Patients requiring interpreters equally exhibited shorter ATP times (152 vs 170 min; p=0.01) and higher stroke severity. There was no significant disadvantage hailing from the LOTE group in OTA times and in any time metrics for subgroup analyses stratified by primary presenter status. However, LOTE patients had poorer 3-month outcomes (mRS ≤2: 46.5% vs 55.4%; p=0.021), which was associated with higher baseline NIHSS and diabetes in adjusted analyses. Conclusion: LOTE patients in SWS undergoing EVT were not disadvantaged in hospital time metrics. Poorer 3-month functional outcomes in LOTE patients highlight the need for targeted strategies addressing risk factors, such as diabetes mellitus.

Indexed as

CEREBRAL BLOOD FLOWSTROKE

Identifiers

PMID40546303
PMCPMC12182037

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.