ArticleFrontiers in neurology2025
Alterations in the functional connectivity of thalamic subregions after basal ganglia stroke.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Modulation of cognitive and motor functions by temporal interference stimulation: a systematic review and meta-analysis of efficacy and variability.Frontiers in psychology · 2026Pooled it
- Neurovascular dysfunction in cerebral small vessel disease: impact on cognition and depression using arterial spin labeling and resting-state fMRI.Brain imaging and behavior · 2026Article
- Dynamic Functional Connectivity Changes in Cortical and Cortico-Striatal Strokes in Mice.CNS neuroscience & therapeutics · 2026Article
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Authors and funding
7 authors.
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Abstract
Background: Motor and cognitive impairments are common symptoms of basal ganglia (BG) stroke, although the underlying neurobiological mechanisms remain unclear. Therefore, we aimed to explore the alterations in functional connectivity (FC) between thalamic subregions post-BG stroke via resting-state functional magnetic resonance imaging (rs-fMRI) measurements. Methods: This cross-sectional study compared 40 patients with BG stroke and 35 healthy controls (HCs). Seed-based FC analysis was performed for 14 thalamic subregions. Correlations between FC changes and Fugl-Meyer Assessment (FMA)/Mini-Mental State Examination (MMSE) scores were assessed. Results: Patients exhibited hyperconnectivity between the left thalamic subregion connected with the sensory cortex (SC_thalamus) and left precuneus ( Conclusion: BG stroke disrupts thalamocortical circuitry at subregional levels, with distinct FC patterns linking to motor/cognitive deficits. These network-level insights may guide targeted neuromodulation therapies. The identified FC alterations could serve as biomarkers for monitoring recovery and personalizing interventions to improve post-stroke rehabilitation outcomes.
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