Evidence map›Paper›PMID 40546021›Full record

ArticleFacts, views & vision in ObGyn2025

The impact of virtual reality technology in the era of See & Treat hysteroscopy: a randomised controlled trial.

Brunella Zizolfi, Virginia Foreste, Maria Giuseppina Trinchillo, Danilo Borrelli, Alessandra Gallo, Maria Chiara De Angelis, Fabiola Nardelli, Attilio Di Spiezio Sardo

Abstract read
In one paragraph

Article in Facts, views & vision in ObGyn, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Virtual reality for pain relief in gynaecological careFacts, views & vision in ObGyn · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Brunella ZizolfiDepartment of Public Health, University of Naples Federico II Faculty of Medicine, Naples, Italy.ORCID 0000-0002-3409-7504
Virginia ForesteDepartment of Public Health, University of Naples Federico II Faculty of Medicine, Naples, Italy.ORCID 0000-0002-1120-4610
Maria Giuseppina TrinchilloDepartment of Public Health, University of Naples Federico II Faculty of Medicine, Naples, Italy.ORCID 0009-0001-9311-0617
Danilo BorrelliDepartment of Public Health, University of Naples Federico II Faculty of Medicine, Naples, Italy.ORCID 0009-0002-0125-075X
Alessandra GalloUnit of Obstetrics and Gynecology, University Hospital "San Giovanni di Dio e Ruggi d'Aragona", Salerno, Italy.
Maria Chiara De AngelisDepartment of Neuroscience, Reproductive Sciences and Dentistry, University of Naples Federico II Faculty of Medicine, Naples, Italy.
Fabiola NardelliDepartment of Public Health, University of Naples Federico II Faculty of Medicine, Naples, Italy.ORCID 0009-0004-9637-832X
Attilio Di Spiezio SardoDepartment of Public Health, University of Naples Federico II Faculty of Medicine, Naples, Italy.ORCID 0000-0001-6485-5735

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In the context of outpatient hysteroscopy (OPH), performing a single procedure integrating the operative and diagnostic part is known as "See & Treat hysteroscopy". The virtual reality (VR) technology provides an immersive virtual environment that can provide a non-invasive analgesic. To date, there is limited evidence regarding its use in the OPH setting. Objectives: To evaluate the feasibility and effectiveness of VR technology for pain and anxiety management in OPH. Methods: Unblinded, prospective, randomised controlled trial, conducted at the Hysteroscopy Unit of the University of Naples "Federico II" between May and July 2024. Women aged 18-70 years, indicated for OPH, were randomised into a control group (standard OPH care) and an intervention group (OPH care with the addition of a VR headset). Main Outcome Measures: Pain and anxiety were assessed through subjective measures: numerical rating scale (NRS) scores before and after the procedure, and objective measures: heart and respiratory rate pre- and during the procedure. Satisfaction, time, and success rates were also evaluated. Results: Overall, 116 women were enrolled. The VR group compared to the control group reported significantly lower mean standard deviation NRS scores for pain [3.9 (2.7) vs. 5.4 (3.0); mean difference 1.5, 95% confidence interval (CI) 0.4 to 2.5] and anxiety [3.2 (2.1) vs. 4.8 (2.8); mean difference 1.6, 95% CI 0.7 to 2.5] respectively. Regarding satisfaction, 96.5% of the VR group would use the headset again, whereas 3.5% requested its removal. All women in the control group desired a distraction. No serious adverse events were reported. Conclusions: VR technology proved feasible and effective for pain and anxiety management in OPH, particularly during operative procedures. What is New?: Its use can support the implementation of the See & Treat philosophy.

Indexed as

Outpatient hysteroscopypain and anxietyvirtual reality technology

Identifiers

PMID40546021
PMCPMC12233116

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.