Evidence map›Paper›PMID 40545557›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2025

Understanding participants' attitudes toward research in the CARE registry.

Thomas J Hoffmann, Janice Y Tsoh, Oanh L Meyer, Marian Tzuang, Bora Nam, Gabriel Fara-On, Daren Huang, Alka M Kanaya, Dolores Gallagher-Thompson, Quyen Vuong and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Understanding participants' attitudes toward research in the CARE registry.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Thomas J HoffmannDepartment of Epidemiology and Biostatistics, Institute for Human Genetics, and Office of Research School of Nursing, University of California, San Francisco, California, USA.
Janice Y TsohDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, California, USA.
Oanh L MeyerDepartment of Neurology, University of California Davis, Sacramento, California, USA.
Marian TzuangDepartment of Community Health Systems, University of California, San Francisco, California, USA.
Bora NamDepartment of Community Health Systems, University of California, San Francisco, California, USA.
Gabriel Fara-OnDepartment of Community Health Systems, University of California, San Francisco, California, USA.
Daren HuangDepartment of Community Health Systems, University of California, San Francisco, California, USA.
Alka M KanayaAsian American Research Center on Health (ARCH), University of California, San Francisco, California, USA.
Dolores Gallagher-ThompsonDepartment of Psychiatry & Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA.
Quyen VuongInternational Children Assistance Network (ICAN), San Jose, California, USA.
Hye-Won ShinInstitute for Memory Impairments and Neurological Disorders, University of California Irvine, Irvine, California, USA.
Va'atausili TofaeonoAmerican Samoa Community Cancer Coalition, Nu'uuli, American Samoa, USA.
Joshua D GrillInstitute for Memory Impairments and Neurological Disorders, University of California Irvine, Irvine, California, USA.
Van Ta ParkAsian American Research Center on Health (ARCH), University of California, San Francisco, California, USA.

Funding

Collaborative Approach for Asian Americans, Native Hawaiians, and Pacific Islanders Research and Education (CARE) 2.0R01AG083926 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Joshua Grill, Van My Ta Park · 2023 to 2026
$12.9M
COVID-19 Effects on the Mental and Physical Health of AAPI Survey Study (COMPASS) IIR24AG063718 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PARK, VAN MY TA · 2019 to 2021
$4.4M
NIA NIH HHS R01 AG083926NIH HHS R01AG083926NIH HHS R24AG063718
6 · The paper itself

Abstract

introductionElucidating barriers and facilitators to research participation is especially important in Asian American, Native Hawaiian, and Pacific Islander (AANHPI) populations, who are significantly underrepresented in Alzheimer's disease and related dementias (ADRD) research.

methodsWe analyzed multilingual data from the 7-item Research Attitude Questionnaire (RAQ) among diverse AANHPI participants across a broad age range in the Collaborative Approach for AANHPI Research and Education (CARE) registry.

resultsUpon enrollment, 10,063 CARE participants were invited to complete the RAQ; 72.3% (7281) did so. The RAQ survey showed that 75.0% had favorable attitudes toward research. In a stepwise model, characteristics associated with a more favorable attitude toward research included identifying as Vietnamese, older age, providing multiple contact methods, living in the Western U.S. region, and having better general health. DISCUSSION: Attitudes toward research differ based on specific characteristics. Certain subpopulations may require more tailored and/or resource-intensive engagement to increase their research participation. HIGHLIGHTS: Understanding research participation barriers is crucial in those underrepresented. Seventy-five percent of Collaborative Approach for Asian Americans, Native Hawaiians and Pacific Islanders Research and Education (CARE) registry members had favorable research attitudes. The study identified characteristics associated with research attitudes. Subpopulations may require more tailored and/or resource-intensive engagement.

Indexed as

Alzheimer DiseaseBiomedical ResearchRegistriesAgedAged, 80 and overAsianFemaleHumansMaleMiddle AgedNative Hawaiian or Pacific IslanderSurveys and QuestionnairesAlzheimer's diseaseAsian AmericansdementiaNative HawaiiansPacific Islandersrecruitment scienceresearch attitudesresearch registry

Identifiers

PMID40545557
PMCPMC12183098

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.