Evidence map›Paper›PMID 40545467›Full record

ArticleZhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery2025

[Disease burden of spinal fractures in China from 1990 to 2021 and temporal trends: A comparative analysis based on the Global Burden of Disease Study 2021].

Hao Wang, Hua Liu, Tianyun Shi, Huaixi Fan, Songkai Li

Abstract readComparative StudyEnglish Abstract
In one paragraph

Article in Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

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0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hao WangFirst Clinical Medical College of Gansu University of Chinese Medicine, Lanzhou Gansu, 730000, P. R. China.
Hua LiuFirst Clinical Medical College of Gansu University of Chinese Medicine, Lanzhou Gansu, 730000, P. R. China.
Tianyun ShiFirst Clinical Medical College of Gansu University of Chinese Medicine, Lanzhou Gansu, 730000, P. R. China.
Huaixi FanFirst Clinical Medical College of Gansu University of Chinese Medicine, Lanzhou Gansu, 730000, P. R. China.
Songkai LiDepartment of Orthopedics, the 940th Hospital of Chinese PLA Joint Logisitcs Support Force, Lanzhou Gansu, 730050, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To analyze the current status and temporal trends of the disease burden of spinal fractures in China from 1990 to 2021 based on data from the Global Burden of Disease Study 2021 (GBD 2021), aiming to provide evidence for developing prevention and treatment strategies. Methods: Epidemiological data on spinal fractures in China, the United States of America (USA), and globally were extracted from the GBD 2021 database. Joinpoint regression models were applied to analyze temporal trends. Age-standardized incidence, prevalence, and disability-adjusted life years (DALYs) rates were calculated, with comparisons of gender- and age-group disparities. Results: In 2021, the number of incident cases, prevalent cases, and DALYs of spinal fractures in China increased by 52.28%, 113.68%, and 106.98%, respectively, compared to 1990. The age-standardized incidence, prevalence, and DALYs rates rose by 11.80%, 16.11%, and 14.79%, respectively. The disease burden escalated significantly with age, peaking in individuals aged ≥75 years. Males exhibited higher age-standardized incidence and DALYs rates than females. Comparative analysis revealed that the age-standardized DALYs rate in China (4.19/100 000) was lower than that in globally (6.62/100 000) and USA (15.92/100 000). However, China showed an upward trend [annual average percentage change (AAPC)=0.19%], contrasting with a declining trend in the USA (AAPC=-0.08%). Conclusion: The escalating disease burden of spinal fractures in China is closely linked to population aging, gender disparities, and insufficient targeted prevention policies. Future strategies should integrate age- and gender-specific interventions, including strengthened osteoporosis prevention, trauma risk control, and big data-driven precision measures, to mitigate this burden.

Indexed as

Cost of IllnessGlobal Burden of DiseaseSpinal FracturesAdolescentAdultAgedAged, 80 and overChildChinaDisability-Adjusted Life YearsFemaleHumansIncidenceMaleMiddle AgedPrevalencedisease burdenSpinal fracturetrend analysis

Identifiers

PMID40545467
PMCPMC12179247

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