Evidence map›Paper›PMID 40545333›Full record

ReviewDental clinics of North America2025

Chronic Oral Complications of Oral Cancer Therapy.

Madison E Richards, Michael T Brennan

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Dental clinics of North America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Madison E RichardsDepartment of Oral Medicine /Oral & Maxillofacial Surgery, Atrium Health Carolinas Medical Center, 1000 Blythe Boulevard, Charlotte, NC 28203, USA.
Michael T BrennanDepartment of Oral Medicine /Oral & Maxillofacial Surgery, Atrium Health Carolinas Medical Center, 1000 Blythe Boulevard, Charlotte, NC 28203, USA; Department of Otolaryngology/Head & Neck Surgery, Wake Forest University School of Medicine, Winston-Salem, NC, USA. Electronic address: Mike.Brennan@atriumhealth.org.

Funding

Long-term Oral Complications of an Established Head and Neck Cancer Cohort- Clinical Registry of Dental Outcomes in Head and Neck Cancer Patients: OraRadU01DE022939 · NIDCR · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI BRENNAN, MICHAEL T, LALLA, RAJESH V. · 2012 to 2023
$16.8M
NIDCR NIH HHS U01 DE022939
6 · The paper itself

Abstract

Head and neck cancer (HNC) patients are uniquely susceptible to adverse oral health outcomes following head and neck radiation therapy (RT). Various risk factors for these oral health outcomes post-RT were identified in the OraRad study, which followed HNC patients from pre-RT to 2 y post-RT. Chronic oral complications include hyposalivation, trismus, dental caries, periodontal disease, tooth loss, exposed bone, and osteoradionecrosis of the jaw. Results from OraRad provide a framework for oral health care providers both in preparing patients for RT and in managing sequelae of RT for best outcomes for the HNC patient population.

Indexed as

Head and Neck NeoplasmsMouth DiseasesRadiation InjuriesChronic DiseaseDental CariesHumansOsteoradionecrosisPeriodontal DiseasesRisk FactorsTooth LossTrismusXerostomiaHead and neck cancerOral cancerOsteoradionecrosisPost-radiationRadiation cariesTooth loss

Identifiers

PMID40545333
PMCPMC13296740

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.