Evidence map›Paper›PMID 40544416›Full record

SynthesisJournal of robotic surgery2025

Postoperative functional complications and quality of life following robot-assisted prostatectomy and radiotherapy in localized prostate cancer: evidence from a systematic review and meta-analysis.

Yang Liu, Yanan Wang, Xi Xiao, Chengyu You, Peng Yu, Qixiang Fang, Yongjin Yang, Zhilong Dong

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Journal of robotic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yang Liu *Department of Urology, The Second Hospital of Lanzhou University, Lanzhou, China.
Yanan Wang *Department of Urology, The Second Hospital of Lanzhou University, Lanzhou, China.
Xi Xiao *Department of Urology, The Second Hospital of Lanzhou University, Lanzhou, China.
Chengyu YouDepartment of Urology, The Second Hospital of Lanzhou University, Lanzhou, China.
Peng YuDepartment of Urology, The Second Hospital of Lanzhou University, Lanzhou, China.
Qixiang FangDepartment of Urology, The Second Hospital of Lanzhou University, Lanzhou, China.
Yongjin YangDepartment of Urology, The Second Hospital of Lanzhou University, Lanzhou, China.
Zhilong DongDepartment of Urology, The Second Hospital of Lanzhou University, Lanzhou, China. dzl19780829@163.com.

Funding

Cuiying Science and Technology Innovation Program CY2024-LC-A01Fundamental Research Funds for Central Universities lzujbky-2023-ct06Gansu Province Joint Research Fund 23JRRA1509Gansu Province Key Talent Program 2023RCXM42Gansu Province Major Science and Technology Special Project 24ZDFA007National Natural Science Foundation of China 82160148
6 · The paper itself

Abstract

To compare patient-reported functional outcomes and health-related quality of life (QoL) after robot-assisted radical prostatectomy (RARP) and radiotherapy (RT) for localised prostate cancer. We systematically searched PubMed, EMBASE, the Cochrane Library and Web of Science (inception to 10 January 2025). Comparative studies reporting urinary, bowel or sexual outcomes were eligible. Pooled relative risks (RRs) and weighted mean differences (WMDs) with 95% confidence intervals (CIs) were calculated using random-effects models. Study quality was assessed with the Newcastle-Ottawa Scale. Seven studies comprising 6 133 men (3625 RARP: 2508 RT) met the inclusion criteria. RARP was associated with significantly higher risks of urinary incontinence (RR = 5.19, 95% CI: 2.03-13.25; P = 0.007) and erectile dysfunction (RR = 1.69, 95% CI: 1.06-2.68; P < 0.05) compared to RT. Functional outcomes favored RT in urinary bother reduction (WMD = -9.04, 95% CI: -17.80 to -0.29), although no significant intergroup differences emerged in bowel domain scores. RT demonstrated superior preservation in sexual function (WMD = -5.91, 95% CI: -8.67 to -3.15), while maintaining comparable fecal urgency rates (RR = 0.42, 95% CI: 0.38-0.48). RT demonstrated superior post-treatment QoL profiles in multiple functional domains compared to RARP for localized prostate cancer, particularly regarding urinary continence and sexual health preservation. These findings can guide shared decision-making regarding treatment choice.

Indexed as

Postoperative ComplicationsProstatectomyProstatic NeoplasmsQuality of LifeRadiotherapyRobotic Surgical ProceduresErectile DysfunctionHumansMaleUrinary IncontinenceLocalized prostate cancerMeta-analysisQuality of lifeRadiotherapyRobot-assisted radical prostatectomy

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.