Evidence map›Paper›PMID 40544185›Full record

ArticleEndocrine2025

Adrenal lesions in patients with abdominal multitrauma.

Anna Kistner, Lisa Kekonius, Jan Calissendorff, Seppo Koskinen, Henrik Falhammar

Erratum issuedAbstract read
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Article in Endocrine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Anna KistnerDepartment of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden. anna.kistner@regionstockholm.se.
Lisa KekoniusDepartment of Nuclear Medicine and Medical Physics,, Karolinska University Hospital, Stockholm, Sweden.
Jan CalissendorffDepartment of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden.
Seppo KoskinenDepartment of Clinical Science, Intervention, and Technology, Division of Radiology, Karolinska Institute, Stockholm, Sweden.
Henrik FalhammarDepartment of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMost adrenal lesions are less than 2 cm and can easily be ignored during primary review of computed tomography (CT)-scans with another question. Furthermore, adrenal lesions, including adrenal hematomas, can easily be missed in patients with multitrauma. We aimed to determine the incidence of adrenal lesions in patients with multitrauma.

methodsThis retrospective, single-center cohort analysis included 1373 patients with multitrauma (71.2% males) with a mean age of 42 (95%CI 41-43) years. One radiologist re-examined all multitrauma CT performed 2013-2017 using thin sliced imaging in at least two depictions. A second radiologist re-examined patients where an abnormality was found. Adrenal abnormalities were labelled adrenal lesions (size ≥10 mm) or hematomas, respectively. Clinical data were collected.

resultsThe adrenal lesion prevalence was 2.7% (37/1373, 78% males, 22% bilateral). Of these 27% (10/37) were mentioned in the radiological report, and in those with a size ≥15 mm (n = 13), 38% (5/13) were mentioned. Of the unilateral adrenal lesions 86% (25/29) were left-sided. In the adrenal lesion group during the mean follow-up time of 75 (61-90) months none had surgery, 6% had hormones measured (all normal), and 7% had repeated adrenal imaging. The adrenal hematoma prevalence was 5.0% (68/1373, 10% bilateral). No patient had both an adrenal hematoma and an adrenal lesion. Of the unilateral hematomas 42% (26/62) were not mentioned. Of the hematomas 77% were right-sided. No patient with adrenal abnormalities had signs of adrenal insufficiency. 30-day survival rates in the adrenal lesion and hematomas groups were similar, but the hematoma group had higher injury severity score, but no longer length of hospital stay.

conclusionsThe prevalence of adrenal tumors was 2.7% and adrenal hematomas 5.0%. Most lesions were not mentioned in the image report. Few had hormonal evaluation or adrenal imaging follow-up. Survival rates were similar between the two groups.

Indexed as

Abdominal InjuriesAdrenal Gland DiseasesAdrenal GlandsHematomaMultiple TraumaAdultFemaleHumansMaleMiddle AgedPrevalenceRetrospective StudiesTomography, X-Ray Computedadrenal hematomasAdrenal incidentalomasadrenal tumorCT imagingfollow-upsurvival

Identifiers

PMID40544185
PMCPMC12464106

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