Evidence map›Paper›PMID 40543627›Full record

ArticleGastrointestinal endoscopy2026

Comparison of fully covered self-expandable metal stents with and without antimigration fins for the management of distal malignant biliary obstruction.

Jacob Bauss, Jad P AbiMansour, Daniel M Simadibrata, Ross Dierkhising, John A Martin, Bret T Petersen, Ryan J Law, Andrew C Storm, Eric J Vargas, Aliana Bofill-Garcia and 2 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Gastrointestinal endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jacob BaussDepartment of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Jad P AbiMansourDepartment of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Daniel M SimadibrataDepartment of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Ross DierkhisingDivision of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota, USA.
John A MartinDepartment of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Bret T PetersenDepartment of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Ryan J LawDepartment of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Andrew C StormDepartment of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Eric J VargasDepartment of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Aliana Bofill-GarciaDepartment of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Barham K Abu DayyehDivision of Digestive and Liver Diseases, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Vinay ChandrasekharaDepartment of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA. Electronic address: chandrasekhara.vinay@mayo.edu.

Funding

Small Molecule Enhancers of Photodynamic Therapy for Skin CancerP01CA084203 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI Brian William Pogue · 2001 to 2026
$27.9M
NCI NIH HHS P01 CA084203
6 · The paper itself

Abstract

BACKGROUND AND

aimsEndoscopic palliation of obstructive jaundice from distal malignant biliary obstruction (dMBO) improves the quality of life of patients. This study aims to compare the clinical outcomes at 6 months after implantation of traditional fully covered self-expandable metal stents (FCSEMSs) versus those with antimigration fins (FCSEMS-AF) in patients with dMBO.

methodsIndividuals undergoing FCSEMS or FCSEMS-AF placement for dMBO from May 2017 to September 2023 were identified. Outcomes included intervention-free stent patency, reintervention rates, time to endoscopic reintervention, clinical success, and adverse events (AEs). Analysis included Kaplan-Meier curves and Cox proportional hazards models.

resultsThe cohort included 215 patients (142 with FCSEMSs and 73 with FCSEMSs-AF). Clinical success was similar in both groups (93.7% in FCSEMSs vs 95.9% in FCSEMSs-AF; P = .500). At 6 months, 84.8% of FCSEMSs had intervention-free patency compared to 77.1% of FCSEMSs-AF (P = .461), with similar rates of AEs (16.2% in FCSEMS and 21.7% in FCSEMS-AF groups; P = .335) and reintervention (16.2% of FCSEMSs and 22.1% of FCSEMSs-AF; P = .324). At 6 months, FCSEMSs-AF had higher rates of stent occlusion (13.2% of FCSEMSs vs 28.3% of FCSEMSs-AF; P = .011) and lower rates of migration (7.6% of FCSEMSs vs 0% of FCSEMSs-AF; P = .011). After adjusting for stent length, FCSEMSs had a higher risk of migration (hazard ratio 12.23 [95% CI, 1.9-78.66]; P = .008) with similar occlusion risk (hazard ratio 0.68 [95% CI, 0.31-1.51]; P = .342).

conclusionsFCSEMSs and FCSEMSs-AF have similar performance characteristics at 6 months; however FCSEMSs were more likely to migrate and had similar occlusion risk after stent length adjustment. These findings can provide insight into the current limitations and help guide future stent design.

Indexed as

Bile Duct NeoplasmsCholestasisJaundice, ObstructivePalliative CareSelf Expandable Metallic StentsAgedAged, 80 and overCholangiopancreatography, Endoscopic RetrogradeFemaleHumansMaleMiddle AgedProsthesis DesignReoperationRetrospective StudiesTreatment Outcome

Identifiers

PMID40543627
PMCPMC12412462

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.