ArticleLangmuir : the ACS journal of surfaces and colloids2025
Cardiomyocyte Growth on Cardiac Infusible Extracellular Matrix-Coated and Annealed Biodegradable Polyurethane Fibers.
Article in Langmuir : the ACS journal of surfaces and colloids, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
Abstract
Biodegradable polyurethane (PU) is a promising biomaterial for tissue repair due to its customizable mechanical properties, high elasticity, biocompatibility, and biodegradability. Electrospun PU fibers are valued for their structural similarity to extracellular matrices but undergo shrinkage under physiological conditions, resulting in morphological changes. This study investigated strategies to mitigate shrinkage and enhance the functionality of PU fibers for the cardiac cell culture. Aligned PU fibers were annealed at varying temperatures (50 and 100 °C) to reduce shrinkage, and then 100 °C-annealed fibers were coated with pig heart-derived infusible extracellular matrix (iECM) to promote H9c2 cell adhesion and growth. Annealing at 100 °C significantly reduced shrinkage of the PU fibers compared to non-annealed and 50 °C-annealed fibers. Thermal annealing led to smaller fiber diameters. The iECM coating increased the surface hydrophilicity and improved H9c2 proliferation. Upregulation of cardiac markers, including
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.