Evidence map›Paper›PMID 40542917›Full record

ArticleArchives of virology2025

Identification and characterization of a novel negative-sense RNA virus infecting Fusarium commune, a fungus causing tobacco root rot.

Huagang Xiao, Yonghui Peng, Kai Teng, Xiangping Zhou, Yansong Xiao, Zhenyu Deng, Qi Huang, Can Wang, Lu Zheng, Jiatao Xie and 1 more

Abstract read
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Article in Archives of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Huagang XiaoNational Key Laboratory of Agricultural Microbiology, The Provincial Key Lab of Plant Pathology of Hubei Province, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan, Hubei, China.
Yonghui PengNational Key Laboratory of Agricultural Microbiology, The Provincial Key Lab of Plant Pathology of Hubei Province, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan, Hubei, China.
Kai TengChina Tobacco Corporation Hunan Company, Changsha, Hunan, China.
Xiangping ZhouChina Tobacco Corporation Hunan Company, Changsha, Hunan, China.
Yansong XiaoChina Tobacco Corporation Hunan Company, Changsha, Hunan, China.
Zhenyu DengChina Tobacco Corporation Hunan Company, Changsha, Hunan, China.
Qi HuangChina Tobacco Corporation Hunan Company, Changsha, Hunan, China.
Can WangChina Tobacco Corporation Hunan Company, Changsha, Hunan, China.
Lu ZhengNational Key Laboratory of Agricultural Microbiology, The Provincial Key Lab of Plant Pathology of Hubei Province, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan, Hubei, China.
Jiatao XieNational Key Laboratory of Agricultural Microbiology, The Provincial Key Lab of Plant Pathology of Hubei Province, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan, Hubei, China.ORCID http://orcid.org/0000-0003-1961-0338
Tianbo LiuChina Tobacco Corporation Hunan Company, Changsha, Hunan, China. tianboliu@126.com.

Funding

Technology Project of Hunan Branch of China National Tobacco Corporation HN2023KJ02
6 · The paper itself

Abstract

The fungal genus Fusarium includes several pathogenic species of significant agricultural importance for tobacco cultivation. In this study, we characterized a novel mycovirus, designated "Fusarium commune mononegavirus 1" (FcMV1), isolated from Fusarium commune strain JF-46. The bipartite genome of FcMV1 comprises two negative-sense RNA segments: RNA1 (6,443 nt) and RNA2 (6,301 nt). RNA1 contains a single open reading frame (ORF1, position nt 102–6098) encoding a 224.5-kDa polyprotein with two conserved functional domains: an RNA-dependent RNA polymerase (RdRp) and a mononegavirus mRNA-capping region V. RNA2 has seven putative ORFs (ORF2-ORF8), with ORF6 predicted to encode a nucleocapsid protein, while the remaining ORFs encode hypothetical proteins of unknown function. A multiple sequence alignment revealed 53.5% identity between the FcMV1 polyprotein and its counterpart in Trichoderma harzianum mononegavirus 2, with the nucleocapsid protein showing 33.4% sequence identity. A phylogenetic tree based on RdRp sequences, constructed using the maximum-likelihood method, positioned FcMV1 within a clade with members of the genus Plasmopamonavirus of the family Mymonaviridae. This is the first report of a negative-sense RNA mycovirus infecting F. commune, expanding our understanding of mycovirus diversity in phytopathogenic fungi.

Indexed as

Fungal VirusesFusariumNegative-Sense RNA VirusesNicotianaPlant DiseasesAmino Acid SequenceGenome, ViralOpen Reading FramesPhylogenyPlant RootsRNA-Dependent RNA PolymeraseRNA, ViralViral ProteinsRNA-Dependent RNA PolymeraseRNA, ViralViral Proteins

Identifiers

PMID40542917

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.